Philippe Pasero

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

60h-index10.0kcitations252works1.32yr avg
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Research Topics

DNA Repair Mechanisms(158), Genomics and Chromatin Dynamics(56), Microtubule and mitosis dynamics(35), Cancer therapeutics and mechanisms(30), CRISPR and Genetic Engineering(27)

Publications252 total

Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High‐Risk Diffuse Large B Cell Lymphoma
Hematological Oncology·2025Open Access
Condensin and topoisomerases cooperate to relieve topological stress at stalled replication forks
2025Open Access
Author response for "Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High-Risk Diffuse Large B Cell Lymphoma"
2025
Slx4 and Fun30/SMARCAD1 coordinate S-phase checkpoint regulation and replication fork protection in response to Top1-DNA crosslinks
2025· 1 citedOpen Access
Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers
Nature Communications·2025· 1 citedOpen Access
Abstract 1168: ADAR1 synthetic lethality in <i>BRCA1/2</i>-mutant tumors defines autocrine interferon poisoning as a targetable vulnerability of cancer cells
Cancer Research·2025
Rapid delivery of RNase H1 enables replication fork progression under stress independently of R-loop resolution
2025Open Access
γ-Aminobutyric Acid-Induced Monocytic Reactive Oxygen Species Impair CD4 Restoration in Treated Adults With HIV-1
The Journal of Infectious Diseases·2025· 1 citedOpen Access
Author response: Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
2025Open Access
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
eLife·2025Open Access
Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma
Blood Neoplasia·2025· 1 citedOpen Access
Transcription-Replication Conflicts and Incomplete Replication as a Cause of Micronuclei-Driven Chromoanagenesis
Methods in molecular biology·2025
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
eLife·2024· 3 citedOpen Access
Author response: Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
2024Open Access
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
2024Open Access
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
2024Open Access
MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling
Nature Communications·2024· 17 citedOpen Access
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
2024Open Access
Rrm3 and Pif1 division of labor during replication through leading and lagging strand G-quadruplex
Nucleic Acids Research·2023· 14 citedOpen Access
Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma
Frontiers in Oncology·2023· 8 citedOpen Access
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Frequent Co-authors

Armelle Lengronne(8), Hélène Tourrière(6), Constance Alabert(6), Andrei Chabes(5), Jérôme Poli(5), Susan M. Gasser(5), Julien Bacal(5), Laure Crabbé(4), Magdalena Skrzypczak(4), Krzysztof Ginalski(4), Yea‐Lih Lin(4), Kenji Shimada(4), Julien N Bianco(4), Maria João Silva(3), Sushma Sharma(3), Antoine Barthe(3), Anne-Lyne Schmitz(3), Yea-Lih Lin(3), Ismaël Padioleau(3), Benjamin Pardo(3)