Kenji Shimada

Friedrich Miescher Institute — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index3.9kcitations198works4.72yr avg
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Research Topics

DNA Repair Mechanisms(31), Analytical Chemistry and Chromatography(20), Genomics and Chromatin Dynamics(18), Fungal and yeast genetics research(17), Metabolism and Genetic Disorders(15)

Publications198 total

Mapping the latent CRBN-molecular glue degrader interactome
2025Open Access
The genetic architecture of the human bZIP interaction network
2025Open Access
Loss of cytoplasmic actin filaments raises nuclear actin levels to drive INO80C-dependent chromosome fragmentation
Nature Communications·2024· 3 citedOpen Access
TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events
Nature Communications·2024· 4 citedOpen Access
The genetic architecture of protein interaction affinity and specificity
Nature Communications·2024· 18 citedOpen Access
Optimization of a deep mutational scanning workflow to improve quantification of mutation effects on protein–protein interactions
BMC Genomics·2024· 3 citedOpen Access
The genetic architecture of protein interaction affinity and specificity
2023· 2 citedOpen Access
Development of Thermal Resistance Evaluation Instrument by Flow Calorimeter
Netsu Bussei·2023Open Access
A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress
The EMBO Journal·2021· 17 citedOpen Access
Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage
Molecular Biology of the Cell·2021· 13 citedOpen Access
The stabilized Pol31–Pol3 interface counteracts Pol32 ablation with differential effects on repair
Life Science Alliance·2021· 6 citedOpen Access
<i>In Vitro</i> -Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4
ACS Chemical Biology·2021· 9 citedOpen Access
Destabilization of the holo-DNA Polδ by loss of Pol32 confers conditional lethality that can be suppressed by stabilizing Pol31-Pol3 interaction
2021Open Access
Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair
Molecular Cell·2021· 55 citedOpen Access
Uncoordinated long-patch base excision repair at juxtaposed DNA lesions generates a lethal accumulation of double-strand breaks
2020· 3 citedOpen Access
DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement
Molecular Cell·2020· 63 citedOpen Access
In Vitro-Evolved Peptides Mimic a Binding Motif of the G-Actin-Binding Protein Thymosin-B4 and Serve as Research Tools
2020· 2 citedOpen Access
Medical treatment system for acute stroke using telestroke in medically under-served areas
臨床画像·2020
Study on the Assembly Technology of Die-First/Face-Down Type FO-PLP
2019· 1 cited
Nuclear Actin and Actin-Binding Proteins in DNA Repair
Trends in Cell Biology·2019· 135 citedOpen Access
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Frequent Co-authors

Susan M. Gasser(22), Susumu Yamato(10), Andrew Seeber(8), Yasushi Hori(6), Manami Fujisawa(6), Philippe Pasero(5), Nicole Hustedt(5), Ragna Sack(4), Yasuo Hirose(4), Hiroyuki Wakabayashi(4), Masaharu Nakajima(4), Anaïs Cheblal(3), Thierry Laroche(2), Yukako Oma(2), Thomas Schleker(2), Kazuto Kugou(2), Kunihiro Ohta(2), Masahiko Harata(2), Jérôme Poli(2), Karl‐Peter Hopfner(2)