Tobias Fuhrer

University of Basel — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index10.1kcitations72works4.32yr avg
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Research Topics

Microbial Metabolic Engineering and Bioproduction(18), Bacterial Genetics and Biotechnology(16), Metabolomics and Mass Spectrometry Studies(15), Gut microbiota and health(14), Amino Acid Enzymes and Metabolism(9)

Publications72 total

Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overload
2025Open Access
Diet-derived LPS determines intestinal IgA induction and repertoire characteristics independently of the microbiota
Immunity·2025· 5 citedOpen Access
A human metabolic map of pharmacological perturbations reveals drug modes of action
Nature Biotechnology·2025· 8 cited
Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients
Journal of Clinical Investigation·2023· 54 citedOpen Access
Ribose 5-phosphate: the key metabolite bridging the metabolisms of nucleotides and amino acids during stringent response in Escherichia coli?
Microbial Cell·2023· 14 citedOpen Access
Role of endogenous adenine in kidney failure and mortality with diabetes
2023· 1 citedOpen Access
Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities
Nature Metabolism·2023· 43 citedOpen Access
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
Immunity·2023· 71 citedOpen Access
A generalized covariate-adjusted top-scoring pair algorithm with applications to diabetic kidney disease stage classification in the Chronic Renal Insufficiency Cohort (CRIC) Study
BMC Bioinformatics·2023Open Access
Plasticity of the adult human small intestinal stoma microbiota
Cell Host & Microbe·2022· 46 citedOpen Access
Inference and Prediction Using Functional Principal Components Analysis: Application to Diabetic Kidney Disease Progression in the Chronic Renal Insufficiency Cohort (CRIC) Study
arXiv (Cornell University)·2022Open Access
Distinct N and C Cross-Feeding Networks in a Synthetic Mouse Gut Consortium
mSystems·2022· 28 citedOpen Access
Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism
Nucleic Acids Research·2022· 19 citedOpen Access
Supplementary Material for: High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study
Figshare·2022Open Access
Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Molecular Systems Biology·2022Open Access
High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study
American Journal of Nephrology·2022· 37 citedOpen Access
Distinct N and C cross-feeding networks in a synthetic mouse gut consortium
2021· 3 citedOpen Access
Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
2021· 6 citedOpen Access
Bifunctional Malic/Malolactic Enzyme Provides a Novel Mechanism for NADPH-Balancing in Bacillus subtilis
mBio·2021· 15 citedOpen Access
Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice
Cell Host & Microbe·2021· 95 cited
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Frequent Co-authors

Uwe Sauer(37), Nicola Zamboni(9), Andrew J. Macpherson(8), Hai Li(6), Mercedes Gomez de Agüero(4), Stephanie C. Ganal‐Vonarburg(4), Kathy D. McCoy(4), Paola Picotti(3), Bärbel Stecher(3), Max Chavarría(3), Vı́ctor de Lorenzo(3), Bahtiyar Yılmaz(3), Peter Schönheit(3), Brian Kwan(3), Kumar Sharma(3), Loki Natarajan(3), Harold I. Feldman(3), Sandra Rupp(2), Yasuhiro Uchimura(2), Siegfried Hapfelmeier(2)