Vera P. Krymskaya

LAM Foundation — United States

Medicine · Health Sciences

41h-index6.2kcitations155works1.22yr avg
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Research Topics

Tuberous Sclerosis Complex Research(84), Eosinophilic Disorders and Syndromes(28), PI3K/AKT/mTOR signaling in cancer(23), Pulmonary Hypertension Research and Treatments(17), Asthma and respiratory diseases(11)

Publications155 total

mTOR dysregulation induces IL-6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis
Nature Communications·2025· 2 citedOpen Access
Extracellular Matrix and Fibroblast Activation in Lymphangioleiomyomatosis
American Journal of Respiratory Cell and Molecular Biology·2025
Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease: An Official American Thoracic Society Research Statement
American Journal of Respiratory and Critical Care Medicine·2025· 2 citedOpen Access
Lymphangioleiomyomatosis Patient Research Priorities Survey (LAM-PREP)
CHEST Pulmonary·2025· 2 citedOpen Access
Extracellular Matrix Proteins and Signaling in Lymphangioleiomyomatosis
American Journal of Respiratory and Critical Care Medicine·2025
mTORC1 Activation in Lung Mesenchyme Drives Alveolar Epithelial Cell Fitness
American Journal of Respiratory and Critical Care Medicine·2025
Unique Transcriptomic and Proteomic Signature of mTORC1 Hyperactivation in Lung Mesenchyme
American Journal of Respiratory and Critical Care Medicine·2025
Lymphangioleiomyomatosis Patient Research Priorities Survey: Developing Patient-centered Research Agenda
American Journal of Respiratory and Critical Care Medicine·2025
Targeting fibroblast–endothelial cell interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics
JCI Insight·2025· 5 citedOpen Access
The Bi-steric Inhibitor RMC-5552 Reduces mTORC1 Signaling and Growth in Lymphangioleiomyomatosis
American Journal of Respiratory Cell and Molecular Biology·2024· 5 citedOpen Access
Repurposing Nitazoxanide for Potential Treatment of Rare Disease Lymphangioleiomyomatosis
Biomolecules·2024· 2 citedOpen Access
Neutrophil-avid nanocarrier uptake by STAT3 dominant-negative hyper-IgE syndrome patient neutrophils
Life Science Alliance·2024· 1 citedOpen Access
Evaluation of the Viability and Utility of Long-Term Stored Human Lymphangioleiomyomatosis(LAM) Lung Samples
2024
Hyperactive Mechanistic Target of Rapamycin Signaling Induces Endothelial Dysfunction and Pulmonary Vascular Remodeling
2024
Kinase-dependent Regulation of Lymphangioleiomyomatosis (LAM)-cell Invasion in Multicellular Human Spheroid Models That Mimic LAM Nodules
2024
Unveiling the Immunosuppressive Symphony: A Cross-talk Between Tsc2 Null Mesenchymal Cells and Lung Macrophage in LAM
2024
DNA Methylation Profiling of Heterogeneous Sporadic LAM and Matched Lung Tissue
American Journal of Respiratory Cell and Molecular Biology·2023· 1 cited
Hyperactive mTORC1 in lung mesenchyme induces endothelial cell dysfunction and pulmonary vascular remodeling
Journal of Clinical Investigation·2023· 17 citedOpen Access
Pleural Fibrosis: Now That’s What mTORC(ing) About
American Journal of Respiratory Cell and Molecular Biology·2023· 2 citedOpen Access
Lost in translation: a neglected mTOR target for lymphangioleiomyomatosis
European Respiratory Review·2023· 8 citedOpen Access
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Frequent Co-authors

Elena A. Goncharova(21), Reynold A. Panettieri(18), Dmitry A. Goncharov(15), Andrew Eszterhas(11), Yassine Amrani(8), Raymond B. Penn(7), Elena N. Atochina‐Vasserman(5), David C. Fajgenbaum(4), Jason R. Ruth(4), Frits van Rhee(4), Daniel J. Noonan(4), Alaina J. Ammit(4), Rebecca Hoffman(4), Thomas S. Uldrick(3), Amy Liu(3), Sheila K. Pierson(3), Christopher S. Nabel(3), Razelle Kurzrock(3), Carla Irani(3), Michael J. Orsini(3)