Elena A. Goncharova

University of California, Davis — United States

Medicine · Health Sciences

37h-index4.7kcitations185works1.62yr avg
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Research Topics

Pulmonary Hypertension Research and Treatments(100), PI3K/AKT/mTOR signaling in cancer(20), Tuberous Sclerosis Complex Research(17), Cardiovascular Function and Risk Factors(14), Protease and Inhibitor Mechanisms(9)

Publications185 total

Endothelial <i>GATA6</i> deficiency suppresses intracellular TLR3-interferon signaling in HPAECs and promotes interferon response in HPASMCs
2025Open Access
Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension
Circulation Research·2025· 2 cited
Lactate dehydrogenase-induced DNA Topoisomerase 1 is a novel regulator of smooth muscle cell proliferation and remodeling in pulmonary arterial hypertension
2025
Abstract 4364408: Protein Arginine Methyltransferase 5 Drives Pulmonary Arterial Remodeling in Pulmonary Arterial Hypertension
Circulation·2025
Abstract 4365999: Knockout of the cytosolic RNA receptor melanoma differentiation-associated protein 5 reduces pulmonary hypertension
Circulation·2025
Deficiency of Smooth Muscle Adar1 Exacerbates Vascular Remodeling and Pulmonary Hypertension
Circulation Research·2025· 2 cited
Noncanonical HIPPO-MST1/2 Promotes Hyperproliferation of Pulmonary Vascular Cells through CDC20
American Journal of Respiratory Cell and Molecular Biology·2025Open Access
PRMT5 Regulates Pulmonary Vascular Smooth Muscle Cell Proliferation and Survival in Pulmonary Arterial Hypertension
American Journal of Respiratory and Critical Care Medicine·2025
Novel Insights Into Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: The Role of Mitochondrial Dysfunction and Cell Cycle Arrest
American Journal of Respiratory and Critical Care Medicine·2025
Actin Cytoskeletal Remodeling Mediates SUN1/ARPC5 Protein Accumulation to Drive Nuclear Architectural Alteration; A Novel Signaling Axis in Pulmonary Hypertension
American Journal of Respiratory and Critical Care Medicine·2025
Non-canonical CDC20-securin Signaling Drives Pulmonary Vascular Cell Hyper-proliferation, Remodeling, and Pulmonary Hypertension
American Journal of Respiratory and Critical Care Medicine·2025
HIPK2 Regulates Pro-proliferative Pro-survival Phenotype of Pulmonary Smooth Muscle Cells in Pulmonary Arterial Hypertension
American Journal of Respiratory and Critical Care Medicine·2025
Non-canonical HIPPO-MST1/2 promotes hyper-proliferation of pulmonary vascular cells through CDC20
2025· 1 citedOpen Access
Abstract 4140612: Non-canonical CDC20 signaling promotes smooth muscle and adventitial fibroblasts hyper-proliferation and remodeling in pulmonary arterial hypertension
Circulation·2024
Mitochondria as a primary determinant of angiogenic modality in pulmonary arterial hypertension
The Journal of Experimental Medicine·2024· 6 citedOpen Access
PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension
American Journal of Physiology-Lung Cellular and Molecular Physiology·2024· 5 cited
Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
Circulation·2024· 18 citedOpen Access
New Kid on the Block: GLI1+ Cells and Pulmonary Arterioles Neomuscularization
Circulation Research·2024Open Access
Loss of the Cytosolic Double Stranded RNA Receptor MDA5 Contributes to Pulmonary Artery Endothelial Cell Dysfunction
2024
LDHA-Lactate Axis in Pulmonary Hypertension: Unraveling the Role of EMILIN1 and TOP1 Lactylation
2024
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Frequent Co-authors

Dmitry A. Goncharov(26), Vera P. Krymskaya(22), Ana L. Mora(11), Reynold A. Panettieri(8), Tatiana V. Kudryashova(7), John Sembrat(7), Jeffrey Baust(7), Yen‐Chun Lai(6), Rebecca Vanderpool(6), Mark T. Gladwin(6), Andressa Peña(6), Andrew Eszterhas(5), Mauricio Rojas(5), Timothy N. Bachman(5), Daniel J. Noonan(4), Horace M. DeLisser(4), Baojun Chang(4), Poay N. Lim(4), Yuanjun Shen(4), Jian Hu(4)