Dirk Schübeler

University of Basel — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

83h-index29.3kcitations163works6.52yr avg
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Research Topics

Epigenetics and DNA Methylation(92), Genomics and Chromatin Dynamics(81), Cancer-related gene regulation(36), RNA modifications and cancer(34), CRISPR and Genetic Engineering(21)

Publications162 total

The genetic architecture of the human bZIP interaction network
2025Open Access
A novel deep learning-based framework reveals a continuum of chromatin sensitivities across transcription factors
2025Open Access
Chromatin-dependent motif syntax defines differentiation trajectories
Molecular Cell·2025· 6 citedOpen Access
Nuclear rerouting of paracrine Fgf3 in source cells represses target genes to pattern morphogen responses
2025Open Access
Nucleosomes specify co-factor access to p53
Molecular Cell·2025· 2 citedOpen Access
Author Correction: Identification of genetic elements that autonomously determine DNA methylation states
Nature Genetics·2025Open Access
Author Correction: Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF
Nature Genetics·2024Open Access
Genome access is transcription factor-specific and defined by nucleosome position
Molecular Cell·2024· 33 citedOpen Access
Chromatin-dependent motif syntax defines differentiation trajectories
2024· 6 cited
Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF
Nature Genetics·2024· 24 citedOpen Access
<scp>EU‐LIFE</scp> charter of independent life science research institutes
FEBS Letters·2024· 1 citedOpen Access
Systematic assessment of ISWI subunits reveals that NURF creates local accessibility for proper CTCF function
2023· 1 citedOpen Access
Cooperation between bHLH transcription factors and histones for DNA access
Nature·2023· 97 citedOpen Access
Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens
Nature Communications·2023· 19 citedOpen Access
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
Nature Structural & Molecular Biology·2023· 39 citedOpen Access
ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
Nature Cell Biology·2023· 41 citedOpen Access
Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation
Nature Genetics·2022· 180 citedOpen Access
DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions
Nature Genetics·2022· 47 citedOpen Access
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
2022· 3 citedOpen Access
Generating specificity in genome regulation through transcription factor sensitivity to chromatin
Nature Reviews Genetics·2022· 153 cited
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Frequent Co-authors

Lukas Burger(13), Michael Stadler(11), C Wirbelauer(8), Michaël Weber(6), Fabio Mohn(6), Mark Groudine(6), Dimos Gaidatzis(5), Vijay Tiwari(5), Arnaud Krebs(5), Antoine H.F.M. Peters(5), Rabih Murr(4), Edward J. Oakeley(3), Robert Ivánek(3), Florian Lienert(3), Paul A. Ginno(3), Silvia Domcke(3), Tuncay Baubec(3), Oliver Bell(3), Dilek Imanci(3), Leslie Hoerner(3)