Ruth Atzmon

Hadassah Academic College — Israel

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index2.6kcitations24works0.02yr avg
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Research Topics

Proteoglycans and glycosaminoglycans research(13), Glycosylation and Glycoproteins Research(8), Fibroblast Growth Factor Research(6), Angiogenesis and VEGF in Cancer(3), Protease and Inhibitor Mechanisms(3)

Publications24 total

Extracellular Sequestration and Release of Fibroblast Growth Factor: A Possible Mechanism for Indirect Angiogenesis
2015· 1 cited
Role of Heparanase-Driven Inflammatory Cascade in Pathogenesis of Diabetic Nephropathy
Diabetes·2014· 87 cited
Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor
Anti-Cancer Drugs·2012· 25 cited
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
Journal of Clinical Investigation·2011· 185 citedOpen Access
Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment
Journal of Biological Chemistry·2008· 175 citedOpen Access
Heparanase processing by lysosomal/endosomal protein preparation
FEBS Letters·2005· 45 citedOpen Access
Site-directed Mutagenesis, Proteolytic Cleavage, and Activation of Human Proheparanase
Journal of Biological Chemistry·2005· 110 citedOpen Access
Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development
Seminars in Cancer Biology·2002· 226 cited
Molecular properties and involvement of heparanase in cancer progression and normal development
Biochimie·2001· 60 cited
Expression Pattern and Secretion of Human and Chicken Heparanase Are Determined by Their Signal Peptide Sequence
Journal of Biological Chemistry·2001· 88 citedOpen Access
Mammalian heparanase as mediator of tumor metastasis and angiogenesis.
PubMed·2000· 53 cited
Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
Nature Medicine·1999· 793 cited
Modulation of Mdm2 Expression and p53-Induced Apoptosis in Immortalized Human Ovarian Granulosa Cells**This work was supported by grants from the Israel Academy of Sciences (to I.V. and A.A.), by the Israeli Ministry of Science (to A.A.), by the Leo and Julia Forchheimer Center of Molecular Genetics at the Weizmann Institute of Science (to A.A.) and by a Grant-in-Aid 0704424 from the Ministry of Education, Science and Culture of Japan (to F.K., K.H., and A.A.).
Endocrinology·1998· 62 cited
Differential effect of components of the extracellular matrix on differentiation and apoptosis
Current Biology·1997· 95 citedOpen Access
Sulfate Moieties in the Subendothelial Extracellular Matrix Are Involved in Basic Fibroblast Growth Factor Sequestration, Dimerization, and Stimulation of Cell Proliferation
Journal of Biological Chemistry·1996· 55 citedOpen Access
Control of Cell Proliferation by Heparan Sulfate and Heparin-Binding Growth Factors
Thrombosis and Haemostasis·1995· 32 cited
Basic fibroblast growth factor is an extracellular matrix component required for supporting the proliferation of vascular endothelial cells and the differentiation of PC12 cells.
The Journal of Cell Biology·1989· 190 citedOpen Access
STRIATED MUSCLE FIBERS DIFFERENTIATE IN PRIMARY CULTURES OF ADULT ANTERIOR PITUITARY CELLS
Endocrinology·1988· 5 citedOpen Access
Serum reduces the TSH content in rat pituitary cells in culture
European Journal of Endocrinology·1985· 1 cited
Thyrotrophin and growth hormone secretion and cell morphology in hypothyroid pituitary cells cultured on a natural extracellular matrix
European Journal of Endocrinology·1983· 11 cited
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Frequent Co-authors

Israël Vlodavsky(23), Tamar Peretz(7), Zvi Fuks(7), Rivka Ishai-Michaeli(5), Eyal Zcharia(5), Michael Elkin(4), Helena Aingorn(4), Yael Friedmann(3), Iris Pecker(3), Orit Goldshmidt(3), Amiram Eldor(3), Rachel Bar‐Shavit(3), O. Spira(3), Amirav Gordon(3), J. Gross(3), Orit Pappo(2), Israel Michal(2), Esther Hermano(2), Ariel M. Rubinstein(2), Amichay Meirovitz(2)