Israël Vlodavsky

Technion – Israel Institute of Technology — Israel

Biochemistry, Genetics and Molecular Biology · Life Sciences

106h-index40.3kcitations794works3.32yr avg
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Research Topics

Proteoglycans and glycosaminoglycans research(540), Glycosylation and Glycoproteins Research(222), Fibroblast Growth Factor Research(213), Protease and Inhibitor Mechanisms(92), Angiogenesis and VEGF in Cancer(89)

Publications794 total

Synthesis, Structure, and Function of Heparan Sulfate Glycopolymers to Investigate Glycosaminoglycan–Protein Interactions
Accounts of Chemical Research·2026Open Access
Heparanase-Neutralizing Monoclonal Antibody (mAb A54) Attenuates Tumor Growth and Metastasis
Cells·2025Open Access
Heparanase-Inhibiting Polymeric Heparan Sulfate Mimetic Attenuates Myeloma Tumor Growth and Bone Metastasis
ACS Applied Bio Materials·2025· 2 cited
Design of Paromomycin and Neomycin as Sulfated and Hydrophobic Glycans to Target Heparanase-Driven Tumor Progression and Metastasis
Journal of Medicinal Chemistry·2025· 4 cited
Correction: Tumor- and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization
Cell Death and Disease·2025Open Access
Synthetic glycol-split heparin tri- and tetrasaccharides provide new insights into structural peculiarities for antiheparanase activity
Bioorganic & Medicinal Chemistry·2024· 3 cited
Tumor- and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization
Cell Death and Disease·2024· 1 citedOpen Access
An integral membrane constitutively active heparanase enhances the tumor infiltration capability of NK cells
OncoImmunology·2024· 5 citedOpen Access
Amphiphilic Heparinoids as Potent Antiviral Agents against SARS-CoV-2
Journal of Medicinal Chemistry·2024· 6 citedOpen Access
Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction
Diabetes·2024· 3 cited
<b>Heparanase Stimulation of Physiological Cardiac Hypertrophy is Suppressed Following Chronic Diabetes Resulting in Cardiac Remodeling and Dysfunction</b>
2024Open Access
<b>Heparanase Stimulation of Physiological Cardiac Hypertrophy is Suppressed Following Chronic Diabetes Resulting in Cardiac Remodeling and Dysfunction</b>
2024Open Access
Impact of heparanase‐2 (Hpa2) on cancer and inflammation: Advances and paradigms
The FASEB Journal·2024· 9 citedOpen Access
Dual T cell receptor/chimeric antigen receptor engineered NK‐92 cells targeting the HPV16 E6 oncoprotein and the tumor‐associated antigen L1CAM exhibit enhanced cytotoxicity and specificity against tumor cells
Journal of Medical Virology·2024· 2 citedOpen Access
Nuclear localization of heparanase 2 (Hpa2) attenuates breast carcinoma growth and metastasis
Cell Death and Disease·2024· 5 citedOpen Access
miR-184 represses β-catenin and behaves as a skin tumor suppressor
Cell Death and Disease·2024· 4 citedOpen Access
Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
Nature Communications·2024· 11 citedOpen Access
A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis
Cells·2024· 8 citedOpen Access
Synthetic Glycol-Split Heparin Tri- and Tetrasaccharides Provide New Insights into Structural Peculiarities for Antiheparanase Activity
SSRN Electronic Journal·2024Open Access
Plasticity of Pancreatic Acinar Cells-Lesson from Hpa2-KO Mice
JSM gastroenterology and hepatology.·2023
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Frequent Co-authors

Neta Ilan(10), Michael Elkin(9), Zvi Fuks(8), Ralph D. Sanderson(7), Yael Friedmann(6), Rivka Ishai-Michaeli(6), Michael Klagsbrun(5), Eyal Zcharia(5), Iris Pecker(4), Jin‐Ping Li(4), Judah Folkman(3), Rafael Fridman(3), Joachim Sasse(3), Helena Aingorn(3), Pnina Bashkin(3), Denis Gospodarowicz(3), Rachel Bar‐Shavit(3), Vishnu C. Ramani(3), Amiram Eldor(3), Adriana Haimovitz‐Friedman(3)