Stewart Bates

Medicine · Health Sciences

17h-index4.3kcitations20works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(19), Cancer Research and Treatments(8), Cell death mechanisms and regulation(4), Ubiquitin and proteasome pathways(4), Epigenetics and DNA Methylation(3)

Publications20 total

E2F-1 Potentiates Cell Death by Blocking Antiapoptotic Signaling Pathways
Molecular Cell·1999· 243 citedOpen Access
Mdm2 binds p73α without targeting degradation
Oncogene·1999· 208 cited
Mechanisms of p53-mediated apoptosis
Cellular and Molecular Life Sciences·1999· 303 citedOpen Access
Reversal of p53-induced cell-cycle arrest
Molecular Carcinogenesis·1999· 17 cited
Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
Oncogene·1998· 173 cited
p14ARF links the tumour suppressors RB and p53
Nature·1998· 915 cited
Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status
Oncogene·1997· 117 cited
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
Genes & Development·1997· 260 citedOpen Access
Perturbation of the p53 response by human papillomavirus type 16 E7
Journal of Virology·1997· 47 citedOpen Access
Regulation and function of the cyclin-dependent kinase inhibitor p16CDKN2.
PubMed·1997· 5 cited
Induction of DNA synthesis and apoptosls are separable funcuons of E2F-1
1997
Differential Activation of Target Cellular Promoters by p53 Mutants with Impaired Apoptotic Function
Molecular and Cellular Biology·1996· 272 citedOpen Access
p53 in signaling checkpoint arrest or apoptosis
Current Opinion in Genetics & Development·1996· 335 citedOpen Access
Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.
The EMBO Journal·1996· 301 citedOpen Access
Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins.
PubMed·1995· 179 cited
Cyclin D1 as a cellular proto-oncogene
Seminars in Cancer Biology·1995· 108 cited
Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product.
The EMBO Journal·1995· 355 citedOpen Access
Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein.
PubMed·1994· 184 cited
CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1.
PubMed·1994· 261 cited
Neoplastic cells obtained from Hodgkin's disease function as accessory cells for mitogen-induced human T cell proliferative responses.
The Journal of Immunology·1984· 31 citedOpen Access

Frequent Co-authors

Karen H. Vousden(13), Andrew C. Phillips(5), David Parry(5), Godefridus J. Peters(5), Gordon Peters(3), Kevin M. Ryan(3), Robert L. Ludwig(2), Laura Bonetta(2), Clive Dickson(2), Kristian Helin(2), Marcia Hall(2), Ignacio Palmero(2), Eiji Hara(2), Emma Hickman(2), Paula A. Clark(1), Francesca J. Stott(1), David J. Mann(1), Sheldon Rowan(1), R Ludwig(1), Ygal Haupt(1)