Sébastien Wälchli

Oslo University Hospital — Norway

Medicine · Health Sciences

36h-index3.5kcitations135works3.22yr avg
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Research Topics

CAR-T cell therapy research(76), Immunotherapy and Immune Responses(33), Immune Cell Function and Interaction(33), Virus-based gene therapy research(22), Cancer Immunotherapy and Biomarkers(16)

Publications135 total

Intrinsically disordered insert from SH2D2A rewires CD19 CAR signaling via Tyr290
2026Open Access
A 3D ovarian cancer metastasis model using a decellularised peritoneal matrix to study therapy response
EBioMedicine·2026Open Access
Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors
Cell Reports Medicine·2025· 3 citedOpen Access
LILRB1-directed CAR-T cells for the treatment of hematological malignancies
Leukemia·2025· 2 citedOpen Access
The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies
2025· 1 cited
Protocol for production of tonic CAR T cells with dasatinib
STAR Protocols·2024· 2 citedOpen Access
A 3D ovarian cancer metastasis model using a decellularized peritoneal matrix to study therapy response
2024
Protocol for the development of a bioluminescent AML-PDX mouse model for the evaluation of CAR T cell therapy
STAR Protocols·2024Open Access
T cells successfully fighting cancer
Open Access Government·2024Open Access
CD20 expression regulates CD37 levels in B-cell lymphoma – implications for immunotherapies
OncoImmunology·2024· 6 citedOpen Access
CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
Cell Reports Medicine·2024· 15 citedOpen Access
Transient TCR-based T cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer
Molecular Therapy·2024· 7 citedOpen Access
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
Journal for ImmunoTherapy of Cancer·2024· 8 citedOpen Access
Enrichment of circulating helper-T (Th) and unswitched memory-B (NSwM-B) cell populations and responsiveness to immune checkpoint blockade (ICB) in microsatellite-stable (MSS)/mismatch repair-proficient (pMMR) colorectal cancer (CRC).
Journal of Clinical Oncology·2024
CD20 expression regulates CD37 levels in B-cell lymphoma – implications for immunotherapies
2023· 3 citedOpen Access
9 Advanced orthotopic ovarian cancer patient-derived xenograft models for improved preclinical evaluation of immunotherapies
Regular and Young Investigator Award Abstracts·2023Open Access
In vitro re-challenge of CAR T cells
Methods in cell biology·2023
Can modulation of autophagy reinvigorate T cells in the elderly?
Ageing and Cancer Research & Treatment·2023Open Access
P611: CD37 AS A MOLECULAR TARGET FOR CAR-T CELLS AGAINST CHRONIC LYMPHOCYTIC LEUKEMIA
HemaSphere·2023Open Access
Determination of CAR T cell metabolism in an optimized protocol
Frontiers in Bioengineering and Biotechnology·2023· 1 citedOpen Access
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Frequent Co-authors

Else Marit Inderberg(11), Kirsten Sandvig(10), Gunnar Kvalheim(8), Gustav Gaudernack(8), Rob Hooft van Huijsduijnen(7), June H. Myklebust(7), Pierre Dillard(6), Hakan Köksal(6), Marit Renée Myhre(6), Erlend B. Smeland(5), Andrés D. Maturana(5), Johanna Olweus(5), Baoyan Bai(4), Kanutte Huse(4), Anne Fåne(4), Nadia Mensali(4), Shun’ichi Kuroda(4), Xavier Espanel(4), Sigrid S. Skånland(4), Weiwen Yang(4)