Rob Hooft van Huijsduijnen

Medicines for Malaria Venture — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

47h-index8.9kcitations100works6.02yr avg
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Research Topics

Protein Tyrosine Phosphatases(40), Galectins and Cancer Biology(23), Malaria Research and Control(18), Cytokine Signaling Pathways and Interactions(12), Computational Drug Discovery Methods(11)

Publications100 total

Global Health Priority Box─Proactive Pandemic Preparedness
ACS Infectious Diseases·2024· 6 citedOpen Access
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks
ACS Infectious Diseases·2022· 33 citedOpen Access
Reassessing therapeutic antibodies for neglected and tropical diseases
PLoS neglected tropical diseases·2020· 33 citedOpen Access
Two successful decades of Swiss collaborations to develop new anti-malarials
Malaria Journal·2019· 11 citedOpen Access
A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria
Malaria Journal·2018· 30 citedOpen Access
Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria
Malaria Journal·2018· 42 citedOpen Access
Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study
The Lancet Infectious Diseases·2018· 140 citedOpen Access
The antimalarial pipeline
Current Opinion in Pharmacology·2018· 76 cited
Malaria
Nature Reviews Disease Primers·2017· 650 citedOpen Access
Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines
PLoS Medicine·2017· 155 citedOpen Access
Erratum to: New developments in anti-malarial target candidate and product profiles
Malaria Journal·2017· 19 citedOpen Access
Both Intrinsic Substrate Preference and Network Context Contribute to Substrate Selection of Classical Tyrosine Phosphatases
Journal of Biological Chemistry·2017· 11 citedOpen Access
New developments in anti-malarial target candidate and product profiles
Malaria Journal·2017· 517 citedOpen Access
Referee report. For: Towards a systems approach for chronic diseases, based on health state modeling [version 1; referees: 2 approved]
Faculty of 1000 Research Ltd·2017Open Access
New Models of Drug Discovery and Development for Neglected Disease Populations
Elsevier eBooks·2016· 1 cited
A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study
Malaria Journal·2016· 125 citedOpen Access
Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma
Acta Neuropathologica Communications·2016· 27 citedOpen Access
Open data in drug discovery and development: lessons from malaria
Nature Reviews Drug Discovery·2016· 27 citedOpen Access
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
PLoS Pathogens·2016· 441 citedOpen Access
Efficacy of OZ439 (artefenomel) against early <i>Plasmodium falciparum</i> blood-stage malaria infection in healthy volunteers
Journal of Antimicrobial Chemotherapy·2016· 102 citedOpen Access
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Frequent Co-authors

Timothy N. C. Wells(7), Jörg J. Möhrle(5), James Whelan(5), Paola Ghersa(5), John F. DeLamarter(5), John F. Bol(5), Jeremy N. Burrows(4), Mark Baker(4), Diane Mathis(4), Agnès Bombrun(4), Sébastien Wälchli(4), Rosanna Pescini Gobert(4), Margaret A. Phillips(3), Wesley C. Van Voorhis(3), Christophe Benoıst(3), Dominique Swinnen(3), Marie-Laure Curchod(3), L.C. van Loon(3), Christian Rommel(3), Stephan Duparc(2)