Michael B. Heskett

University of California, Los Angeles — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index263citations37works2.62yr avg
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Research Topics

RNA Research and Splicing(11), Cancer-related molecular mechanisms research(8), RNA modifications and cancer(8), Epigenetics and DNA Methylation(6), Cancer Genomics and Diagnostics(5)

Publications37 total

Autosomal Allelic Inactivation: Variable Replication and Dosage Sensitivity
2025Open Access
Myc and Kras cooperate in adult acinar cells to drive phenotypic heterogeneity, metastasis, and therapeutic resistance in a novel pancreatic cancer mouse model
2025· 2 citedOpen Access
Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer
Nature Cancer·2025· 24 citedOpen Access
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immuneACCESS·2024
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
eLife·2024· 1 citedOpen Access
Author response: ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
2024Open Access
Author response: ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
2024Open Access
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
2024Open Access
Reviewer #2 (Public Review): ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
2024Open Access
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
2024Open Access
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
eLife·2024· 4 citedOpen Access
Abstract A061: A novel genetically engineered mouse model of Myc-driven pancreatic cancer recapitulates phenotypic heterogeneity, metastasis, and therapy resistance seen in clinical populations
Cancer Research·2024
Characterization of methylation status of the nuclear hormone receptor <i>DAX-1</i> in human cancer
2023Open Access
ASAR lncRNAs Control DNA Replication Timing Through Interactions with Multiple hnRNP/RNA Binding Proteins
SSRN Electronic Journal·2023Open Access
Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability
Nature Communications·2022· 28 citedOpen Access
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
2022· 2 citedOpen Access
Epigenetic Control of Hundreds of Chromosome-Associated lncRNA Genes Essential for Replication and Stability
2022Open Access
An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
Cell Reports Medicine·2022· 51 citedOpen Access
Differential Allelic Expression among Long Non-Coding RNAs
Non-Coding RNA·2021· 5 citedOpen Access
The Feasibility of Patient-Specific Circulating Tumor DNA Monitoring throughout Multi-Modality Therapy for Locally Advanced Esophageal and Rectal Cancer: A Potential Biomarker for Early Detection of Subclinical Disease
Diagnostics·2021· 13 citedOpen Access
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Frequent Co-authors

Paul T. Spellman(23), Mathew J. Thayer(15), Phillip A. Yates(11), Leslie G. Smith(10), Texas State Library and Archives Commission. State and Local Records Managment Division.(9), Christopher Boniface(7), Shamilene Sivagnanam(5), Lisa M. Coussens(5), Carl Pelz(4), Kevin MacPherson‐Hawthorne(4), Patrick J. Worth(4), Ellen M. Langer(4), Isabel A. English(4), Motoyuki Tsuda(4), Terry K. Morgan(4), Rosalie C. Sears(4), Allison Creason(3), Courtney B. Betts(3), Elmar Bucher(3), Koei Chin(3)