Paul T. Spellman

University of California, Los Angeles — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

108h-index136.8kcitations456works2.82yr avg
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Research Topics

Cancer Genomics and Diagnostics(157), Bioinformatics and Genomic Networks(41), Gene expression and cancer classification(39), RNA Research and Splicing(35), RNA modifications and cancer(32)

Publications344 total

Autosomal Allelic Inactivation: Variable Replication and Dosage Sensitivity
2025Open Access
Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients
Nature Communications·2025· 1 citedOpen Access
Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles
UNC Libraries·2025Open Access
Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles
Scientific Reports·2025· 2 citedOpen Access
Methylation dynamics in the decades preceding acute myeloid leukaemia
2025· 1 citedOpen Access
Advancing Precision Health Discovery in a Genetically Diverse Health System
2025· 1 citedOpen Access
Abstract 6608: Integrating HCMI models and tumors with CCLE and TCGA: Advancing cancer modeling and precision oncology
Cancer Research·2025
Abstract 6358: Single cell transcriptional dynamics in the HCMI cancer model collection
Cancer Research·2025
Abstract 4005: Integrative clinical and molecular characterization of an international community resource of organoid models of human cancer
Cancer Research·2025
Abstract 3882: Patterns of genomic patient-model conservation and evolution in the Human Cancer Models Initiative (HCMI) next-generation cancer model resource
Cancer Research·2025
Abstract 1165: The landscape of molecular targets across 665 next-generation cancer models in the human cancer models initiative identifies opportunities for improved therapy and overcoming resistance
Cancer Research·2025
Abstract B025: Integrative clinical and molecular analysis of 665 next-generation in vitro cancer models generated by the the Human Cancer Models Initiative (HCMI) for advancing precision medicine and functional drug discovery
Cancer Research·2025· 1 cited
Mixed ctDNA dynamics and decreased detection rates in early-stage lung cancer patients during radiation treatment
SSRN Electronic Journal·2025Open Access
Supplementary Figures from The History of Chromosomal Instability in Genome-Doubled Tumors
2024Open Access
Data from The History of Chromosomal Instability in Genome-Doubled Tumors
2024Open Access
Supplementary Table S1 from The History of Chromosomal Instability in Genome-Doubled Tumors
2024Open Access
Supplementary Methods from The History of Chromosomal Instability in Genome-Doubled Tumors
2024Open Access
Multiplex imaging of localized prostate tumors reveals altered spatial organization of AR-positive cells in the microenvironment
iScience·2024· 10 citedOpen Access
The History of Chromosomal Instability in Genome-Doubled Tumors
Cancer Discovery·2024· 10 citedOpen Access
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
eLife·2024· 1 citedOpen Access
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Frequent Co-authors

Joe W. Gray(20), Gad Getz(11), Gordon B. Mills(9), Nicholas J. Wang(9), Eric A. Collisson(8), John N. Weinstein(7), Lakshmi R. Jakkula(6), Heidi S. Feiler(6), Gavin Sherlock(6), Rehan Akbani(6), Pavana Anur(6), Laura M. Heiser(6), Patrick O. Brown(5), David Botstein(5), Elizabeth Purdom(5), Michael S. Lawrence(5), Stacey Gabriel(5), Alvis Brāzma(5), Catherine A. Ball(5), Richard M. Neve(5)