Laura M. Heiser

Portland State University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index15.8kcitations293works1.82yr avg
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Research Topics

Cancer Genomics and Diagnostics(39), HER2/EGFR in Cancer Research(37), Single-cell and spatial transcriptomics(37), Bioinformatics and Genomic Networks(31), Cell Image Analysis Techniques(28)

Publications292 total

Growth factors maintain intratumoral heterogeneity and drive therapeutic resistance in triple-negative breast cancer
Cell Reports·2025Open Access
Temporal reassignment and correspondence evaluation with quality control for time-course imaging of 3D cell culture
Cell Reports Methods·2025Open Access
Neoplastic Immune Mimicry Potentiates Breast Tumor Progression
Cancer Research·2025Open Access
Oncostatin M orchestrates collective epithelial migration via HIF1A activation
2025Open Access
Microenvironmental signals combine to induce non-additive molecular and phenotypic responses in mammary epithelial cells
iScience·2025Open Access
Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories
Cell·2025· 23 citedOpen Access
Abstract A028: Automated Rule Synthesis from Literature for Agent-Based Modeling of the Tumor Microenvironment
Clinical Cancer Research·2025
Abstract A027: Multiscale systems approach to target tumor ecosystem responses for therapeutic benefit
Clinical Cancer Research·2025
Axon targeting of transcriptionally distinct pioneer neurons is regulated by retinoic acid signaling
Nature Communications·2025Open Access
Association of rapid progression on CDK4/6 inhibitor (CDKi) for metastatic HR+HER2- breast cancer (mHRBC) with genomic, proteomic, and immune microenvironment alterations.
Journal of Clinical Oncology·2025
1681 Patient-Derived Organoids of anal cancer as a translational tumor model
Radiotherapy and Oncology·2025
Abstract LB178: Neoplastic immune mimicry is a generalizable phenomenon in breast cancer and epithelial CD69 enables early tumor progression
Cancer Research·2025
Abstract 5341: Duration of CDK4/6 inhibitor (CDKi) treatment in metastatic HR+ HER2- breast cancer (mHRBC) is associated with changes in AKT pathway protein expression
Cancer Research·2025
Abstract 3703: Cell identity revealed by precise cell cycle state mapping links data modalities
Cancer Research·2025
Integrative Analysis of EGF, OSM, and TGFB Signaling Pathways Reveals Synergistic Mechanisms Driving Cell Motility Through CXCR2 Chemotactic Signaling and CREB Activation
2025Open Access
Data from Senescent Cell–Derived Extracellular Vesicles Inhibit Cancer Recurrence by Coordinating Immune Surveillance
2025Open Access
Supplementary Table S1 from Senescent Cell–Derived Extracellular Vesicles Inhibit Cancer Recurrence by Coordinating Immune Surveillance
2025Open Access
Supplementary Table S4 from Senescent Cell–Derived Extracellular Vesicles Inhibit Cancer Recurrence by Coordinating Immune Surveillance
2025Open Access
Supplementary Table S2 from Senescent Cell–Derived Extracellular Vesicles Inhibit Cancer Recurrence by Coordinating Immune Surveillance
2025Open Access
Supplementary Data and legends from Senescent Cell–Derived Extracellular Vesicles Inhibit Cancer Recurrence by Coordinating Immune Surveillance
2025Open Access
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Frequent Co-authors

Joe W. Gray(32), Gordon B. Mills(16), Paul T. Spellman(15), James E. Korkola(13), Nicholas J. Wang(10), Heidi S. Feiler(9), Mark Dane(7), Elmar Bucher(7), Zhi Hu(6), Tiera Liby(6), Nora Bayani(5), Peter K. Sorger(5), Sean M. Gross(5), Agostina Nardone(5), Mothaffar F. Rimawi(5), Susan G. Hilsenbeck(5), Rachel Schiff(5), Carol L. Colby(5), Yiling Lu(4), George Thomas(4)