Bibi Kassim

Allen Institute for Brain Science — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index5.1kcitations39works0.82yr avg
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Research Topics

Epigenetics and DNA Methylation(20), Genomics and Chromatin Dynamics(13), Single-cell and spatial transcriptomics(7), Genetics and Neurodevelopmental Disorders(7), Genetic Associations and Epidemiology(6)

Publications39 total

Heterogeneous epigenetic variation converges on splicing dysregulation in opioid addiction
2025
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders
UNC Libraries·2025Open Access
Single chromatin fiber profiling and nucleosome position mapping in the human brain
Cell Reports Methods·2024· 4 citedOpen Access
Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia
UNC Libraries·2024Open Access
Functional annotation of rare structural variation in the human brain
Carolina Digital Repository (University of North Carolina at Chapel Hill)·2024Open Access
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling
Molecular Cell·2022· 31 citedOpen Access
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Nature Genetics·2022· 49 citedOpen Access
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling
2022· 4 citedOpen Access
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains
Nature Neuroscience·2022· 66 citedOpen Access
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose
Molecular Psychiatry·2022· 17 citedOpen Access
Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models
Molecular Psychiatry·2022· 36 citedOpen Access
Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions
Nature Communications·2021· 26 citedOpen Access
NEURON-SPECIFIC CHROMOSOMAL MEGADOMAIN ORGANIZATION IS ADAPTIVE TO RECENT RETROTRANSPOSON EXPANSIONS
2021Open Access
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders
Nature Communications·2021· 104 citedOpen Access
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid dependence
2021· 2 citedOpen Access
Acetylated Chromatin Domains Link Chromosomal Organization to Cell- and Circuit-level Dysfunction in Schizophrenia and Bipolar Disorder
2021· 2 citedOpen Access
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection
Stem Cell Reports·2021· 55 citedOpen Access
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
Scientific Data·2020· 325 citedOpen Access
Epigenomic regulation in psychosis
Oxford University Press eBooks·2020
Common genetic variation in humans impacts <i>in vitro</i> susceptibility to SARS-CoV-2 infection
2020· 8 citedOpen Access
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Frequent Co-authors

Schahram Akbarian(38), Yan Jiang(21), Barbara K. Lipska(18), Panos Roussos(17), Kiran Girdhar(16), Jaroslav Bendl(16), Royce Park(15), Jennifer Wiseman(15), Behnam Javidfar(15), Gabriel E. Hoffman(14), Mette A. Peters(13), Elizabeth Zharovsky(13), Olivia Devillers(13), Marina Iskhakova(13), Vahram Haroutunian(12), Chang-Gyu Hahn(12), Elie Flatow(11), John F. Fullard(11), Hyejung Won(10), David A. Lewis(10)