Henry A. Lester

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

98h-index31.7kcitations468works1.12yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(214), Ion channel regulation and function(189), Receptor Mechanisms and Signaling(182), Neuroscience and Neuropharmacology Research(122), Neuroscience and Neural Engineering(52)

Publications467 total

Hydrogel Encapsulation of a Designed Fluorescent Protein Biosensor for Continuous Measurements of Sub-100 nM Nicotine
ACS Applied Bio Materials·2025
How many SARS-CoV-2 “viroporins” are really ion channels?
UNC Libraries·2025Open Access
Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda
Nicotine & Tobacco Research·2025· 1 cited
Simulating early steps in nicotine dependence: Pharmacokinetics, activation, and chaperoning of nicotinic receptors
Molecular Pharmacology·2025· 4 cited
Hydrogel encapsulation of a designed fluorescent protein biosensor for continuous measurements of sub-100 nanomolar nicotine
2024· 1 citedOpen Access
Correspondence of fentanyl brain pharmacokinetics and behavior measured via engineering opioids biosensors and computational ethology
2024· 1 citedOpen Access
NOISE CONTROL GUIDANCE FOR INDUSTRY
2024Open Access
Apropos Students Temporal Exam Effort and Performance
2024Open Access
REVISION OF THE NOISE GUIDES 1 & 2 AND 3 TO 8 THAT SUPPORT THE NOISE AT WORK REGULATIONS 1989
2024
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids
Protein Engineering Design and Selection·2024· 4 citedOpen Access
Antidepressants enter cells, organelles, and membranes
Neuropsychopharmacology·2023· 8 citedOpen Access
Successful Cessation Programs that Reduce Comorbidity may Explain Surprisingly Low Smoking Rates among Hospitalized COVID-19 Patients
Qeios·2023Open Access
β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats
eNeuro·2023· 9 citedOpen Access
Human α6β4 Nicotinic Acetylcholine Receptor: Heterologous Expression and Agonist Behavior Provide Insights into the Immediate Binding Site
Molecular Pharmacology·2023· 4 cited
Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane
Journal of Neuroscience·2023· 16 citedOpen Access
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids
2023· 4 citedOpen Access
Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
eLife·2022· 3 citedOpen Access
How many SARS-CoV-2 “viroporins” are really ion channels?
Communications Biology·2022· 22 citedOpen Access
Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor
Journal of the American Chemical Society·2022· 16 cited
Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane
2022· 2 citedOpen Access
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Frequent Co-authors

Norman Davidson(20), Cesar Labarca(11), Paulo Kofuji(6), Sheri McKinney(5), Dennis A. Dougherty(5), Raad Nashmi(4), Purnima Deshpande(4), Baljit S. Khakh(4), John Guastella(3), Johannes Schwarz(3), Paul Whiteaker(3), Michael J. Marks(3), Wenge Zhong(3), Vanessa J. Auld(3), Alan L. Goldin(3), Robert Dunn(3), Michael W. Quick(3), Mark W. Nowak(3), Hermann Lübbert(3), Linda Czyzyk(2)