Francis Combes

SINTEF — Norway

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index798citations30works2.42yr avg
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Research Topics

RNA Interference and Gene Delivery(13), Immunotherapy and Immune Responses(10), Immune cells in cancer(5), Advanced biosensing and bioanalysis techniques(4), Virus-based gene therapy research(4)

Publications30 total

Attempt to Identify Extracellular Vesicles Derived From the Blood-Brain Barrier in Peripheral Blood
Journal of Trial and Error·2025Open Access
Antisense oligonucleotide-based switches for conditional translation of synthetic mRNA
Molecular Therapy — Nucleic Acids·2025Open Access
Using nucleolytic toxins as restriction enzymes enables new RNA applications
Nucleic Acids Research·2024· 2 citedOpen Access
Rapid and scalable detection of synthetic mRNA byproducts using polynucleotide phosphorylase and polythymidine oligonucleotides
RNA Biology·2024· 2 citedOpen Access
Urea supplementation improves mRNA in vitro transcription by decreasing both shorter and longer RNA byproducts
RNA Biology·2024· 8 citedOpen Access
CCDC 2178256: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics
Biomaterials·2022· 16 citedOpen Access
Transient Lymph Node Immune Activation by Hydrolysable Polycarbonate Nanogels
Advanced Functional Materials·2022· 32 citedOpen Access
Regulatory guidelines and preclinical tools to study the biodistribution of RNA therapeutics
Advanced Drug Delivery Reviews·2022· 56 citedOpen Access
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators
Journal of the American Chemical Society·2021· 62 citedOpen Access
A paradigm shift in cancer nanomedicine: from traditional tumor targeting to leveraging the immune system
Drug Discovery Today·2021· 23 citedOpen Access
Corticosteroids and mRNA Vaccines: A Word of Caution
Molecular Therapy·2021· 1 citedOpen Access
Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs
Molecular Therapy·2021· 43 citedOpen Access
In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation
Molecular Therapy·2020· 32 citedOpen Access
Corticosteroids and cellulose purification improve respectively the in vivo translation and vaccination efficacy of self-amplifying mRNAs
2020· 1 citedOpen Access
Imidazoquinoline-Conjugated Degradable Coacervate Conjugate for Local Cancer Immunotherapy
ACS Biomaterials Science & Engineering·2020· 18 citedOpen Access
Immune cells as tumor drug delivery vehicles
Journal of Controlled Release·2020· 91 citedOpen Access
Mononuclear but Not Polymorphonuclear Phagocyte Depletion Increases Circulation Times and Improves Mammary Tumor-Homing Efficiency of Donor Bone Marrow-Derived Monocytes
Cancers·2019· 9 citedOpen Access
Improving the Repeatability and Efficacy of Intradermal Electroporated Self-Replicating mRNA
Molecular Therapy — Nucleic Acids·2019· 19 citedOpen Access
Corrigendum to “mRNA therapeutics deliver a hopeful message” [Nano Today 23 (2018) 16–39]
Nano Today·2019
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Frequent Co-authors

Niek N. Sanders(18), Zifu Zhong(11), Séan Mc Cafferty(11), Hanne Huysmans(8), Joyca De Temmerman(8), Stefan Lienenklaus(7), Lutz Nuhn(5), Sunil A. David(5), Bruno G. De Geest(5), Kim Deswarte(4), Bart N. Lambrecht(4), Evelyne Meyer(4), João Portela Catani(3), Sascha Schmitt(3), Judith Stickdorn(3), Christian Czysch(3), Jana De Vrieze(3), Sabah Kasmi(3), Carolina Medina‐Montano(3), Pia Winterwerber(3)