Shing Jen Tai

Children's Hospital of Philadelphia — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index2.6kcitations14works0.02yr avg
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Research Topics

Virus-based gene therapy research(8), Blood Coagulation and Thrombosis Mechanisms(8), Hemophilia Treatment and Research(7), CAR-T cell therapy research(4), Viral Infectious Diseases and Gene Expression in Insects(4)

Publications14 total

Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality
Journal of Clinical Investigation·2008· 38 citedOpen Access
A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X
Journal of Thrombosis and Haemostasis·2008· 32 cited
A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X
Journal of Thrombosis and Haemostasis·2008· 9 citedOpen Access
Murine Model of Suppressed Intrinsic Pathway Using a FX Variant: FX Roma.
Blood·2005
A genetic approach toward defining the role of Factor X in development and coagulation
2005Open Access
Expression of Blood Coagulation Factor X Is Not Liver-Restricted.
Blood·2004
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B
Blood·2003· 744 citedOpen Access
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
Nature Genetics·2000· 1.0k cited
#513 Muscle targeted adeno-associated viral vector mediated gene therapy for hemophilia B
Journal of Pediatric Hematology/Oncology·1998
Adeno-Associated Viral Vector-Mediated Gene Transfer of Human Blood Coagulation Factor IX Into Mouse Liver
Blood·1998· 186 cited
Adeno-Associated Viral Vector-Mediated Gene Transfer of Human Blood Coagulation Factor IX Into Mouse Liver
Blood·1998· 7 cited
Human Factor IX Corrects the Bleeding Diathesis of Mice With Hemophilia B
Blood·1998· 129 citedOpen Access
Human Factor IX Corrects the Bleeding Diathesis of Mice With Hemophilia B
Blood·1998· 7 cited
Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus
Proceedings of the National Academy of Sciences·1997· 472 citedOpen Access

Frequent Co-authors

Katherine A. High(14), Roland W. Herzog(8), J. Nathan Hagstrom(6), Linda B. Couto(5), Szu‐Hao Kung(4), Paris Margaritis(4), Catherine S. Manno(3), Krishna J. Fisher(3), Gary J. Kurtzman(3), K. Chu(3), Mark A. Kay(2), Margaret V. Ragni(2), Peter J. Larson(2), Alan McClelland(2), Bertil Glader(2), Ah Keng Chew(2), Valder R. Arruda(2), Ciaran D. Scallan(2), Erik D. Skarsgard(2), Alan W. Flake(2)