Afshin Samali

Science Foundation Ireland — Ireland

Biochemistry, Genetics and Molecular Biology · Life Sciences

72h-index32.2kcitations258works4.92yr avg
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Research Topics

Endoplasmic Reticulum Stress and Disease(113), Autophagy in Disease and Therapy(72), Cell death mechanisms and regulation(61), Heat shock proteins research(28), RNA Interference and Gene Delivery(27)

Publications256 total

Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly
Cell Death and Differentiation·2025· 2 citedOpen Access
Multiomics Integration of Parkinson’s Disease Datasets Reveals Unexpected Roles of IRE1 in Its Pathology
International Journal of Molecular Sciences·2025Open Access
A trackable trinuclear platinum complex for breast cancer treatment
Nucleic Acids Research·2025· 2 citedOpen Access
Correction: Aghaei et al. The Role of BiP and the IRE1α-XBP1 Axis in Rhabdomyosarcoma Pathology. Cancers 2021, 13, 4927
Cancers·2025Open Access
PRDX-2 modulates mitochondria-ER communication and UPR signalling in response to exercise
Free Radical Biology and Medicine·2025
Improving glioblastoma treatment with imaging, radiotherapy, drug delivery, and therapeutic systems
Device·2025· 5 citedOpen Access
PERK orchestrates MERCS formation and mitochondrial remodelling promoting physiological adaptations during adaptive UPR signalling
2025Open Access
Redox regulation of UPR signalling and mitochondrial ER contact sites
Cellular and Molecular Life Sciences·2024· 35 citedOpen Access
Correction: Dastghaib et al. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells. Cells 2020, 9, 2339
Cells·2024· 2 citedOpen Access
MultiOmicsIntegrator: a nextflow pipeline for integrated omics analyses
Bioinformatics Advances·2024· 3 citedOpen Access
Insights into the structure and function of the RNA ligase RtcB
Cellular and Molecular Life Sciences·2023· 7 citedOpen Access
Supplementary Table 1 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Data from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Supplementary Table 1 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Data from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Supplementary Figures 1-7 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Supplementary Figure Legends 1-7 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Supplementary Methods from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Supplementary Figures 1-7 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
Supplementary Methods from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells
2023Open Access
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Frequent Co-authors

Adrienne M. Gorman(16), Éva Szegezdi(8), Sten Orrenius(8), Susan E. Logue(7), Sanjeev Gupta(7), Sandra Healy(6), Richard Jäger(5), Éric Chevet(4), Katarzyna Mnich(3), Aitor Almanza(3), Patrizia Agostinis(3), Emma C. Madden(3), Claudio Hetz(3), Boris Zhivotovsky(3), John B. Patterson(3), Svetlana Saveljeva(3), Shane Deegan(3), Simone Fulda(2), Joya Chandra(2), Dimitrios Doultsinos(2)