Shane Deegan

Ollscoil na Gaillimhe – University of Galway — Ireland

Medicine · Health Sciences

12h-index7.2kcitations24works0.02yr avg
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Research Topics

Autophagy in Disease and Therapy(15), Endoplasmic Reticulum Stress and Disease(11), Mitochondrial Function and Pathology(5), Cell death mechanisms and regulation(2), Microfluidic and Capillary Electrophoresis Applications(2)

Publications22 total

Correction: Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β
Cell Death and Disease·2020Open Access
Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β
Cell Death and Disease·2019· 49 citedOpen Access
The Unfolded Protein Response in Breast Cancer
Cancers·2018· 85 citedOpen Access
A microfluidic fluidized bed to capture, amplify and detect bacteria from raw samples
Methods in cell biology·2018· 9 cited
A new microfluidic approach for the one-step capture, amplification and label-free quantification of bacteria from raw samples
Chemical Science·2016· 68 citedOpen Access
Label-free optical detection of molecular and cellular binding on reflectionless glass
2016
Exploitation of Glycobiology in Anti-Adhesion Approaches against Biothreat Agents
Journal of Bioterrorism & Biodefense·2016· 4 citedOpen Access
Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity
Oncogene·2015· 62 citedOpen Access
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Figshare·2015Open Access
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Figshare·2015Open Access
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Figshare·2015Open Access
A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy
Biochemical and Biophysical Research Communications·2014· 54 cited
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Autophagy·2014· 58 citedOpen Access
ER stress responses in the absence of apoptosome: A comparative study in CASP9 proficient vs deficient mouse embryonic fibroblasts
Biochemical and Biophysical Research Communications·2014· 2 cited
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Figshare·2014Open Access
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Figshare·2014Open Access
The molecular characterization of ER stress-induced autophagy and cell death
Arrow@dit (Dublin Institute of Technology)·2012· 1 citedOpen Access
NOXA contributes to the sensitivity of PERK‐deficient cells to ER stress
FEBS Letters·2012· 34 citedOpen Access
Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress
Cellular and Molecular Life Sciences·2012· 269 citedOpen Access
Assays for Detecting the Unfolded Protein Response
Methods in enzymology on CD-ROM/Methods in enzymology·2011· 49 cited
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Frequent Co-authors

Afshin Samali(17), Sanjeev Gupta(12), Susan E. Logue(9), Svetlana Saveljeva(8), Karolina Pakos‐Zebrucka(6), Peter Vandenabeele(6), Mathieu J.M. Bertrand(6), Adrienne M. Gorman(5), Katarzyna Mnich(3), Lokesh Joshi(3), Iago Pereiro(2), Amel Bendali(2), Sanae Tabnaoui(2), Lucile Alexandre(2), Jana Srbová(2), Zuzana Bı́lková(2), Jean‐Louis Viovy(2), Laurent Malaquin(2), Bruno Dupuy(2), Stéphanie Descroix(2)