Jochen Kuhse

Heidelberg University — Germany

Neuroscience · Life Sciences

33h-index5.5kcitations65works4.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(49), Receptor Mechanisms and Signaling(30), Ion channel regulation and function(17), Nicotinic Acetylcholine Receptors Study(17), Photoreceptor and optogenetics research(7)

Publications65 total

Is the Activation of the Postsynaptic Ligand Gated Glycine- or GABAA Receptors Essential for the Receptor Clustering at Inhibitory Synapses?
Biomedicines·2025Open Access
Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer’s Disease
International Journal of Molecular Sciences·2024· 8 citedOpen Access
Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate
International Journal of Molecular Sciences·2023· 14 citedOpen Access
GEGEN DAS GROSSE VERGESSEN
University Library Heidelberg·2021Open Access
Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model
Molecular and Cellular Neuroscience·2021· 19 cited
Artemisinin-treatment in pre-symptomatic APP-PS1 mice increases gephyrin phosphorylation at Ser270: a modification regulating postsynaptic GABA<sub>A</sub>R density
Biological Chemistry·2021· 11 citedOpen Access
Binding of gephyrin to microtubules is regulated by its phosphorylation at Ser270
Histochemistry and Cell Biology·2021· 7 citedOpen Access
Amyloid-β Fosters p35/CDK5 Signaling Contributing to Changes of Inhibitory Synapses in Early Stages of Cerebral Amyloidosis
Journal of Alzheimer s Disease·2020· 10 cited
Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer’s disease amyloidosis
PLoS ONE·2019· 85 citedOpen Access
Gephyrin: a key regulatory protein of inhibitory synapses and beyond
Histochemistry and Cell Biology·2018· 68 cited
Table of Contents
American Journal Of Pathology·2016Open Access
Biphasic Alteration of the Inhibitory Synapse Scaffold Protein Gephyrin in Early and Late Stages of an Alzheimer Disease Model
American Journal Of Pathology·2016· 36 citedOpen Access
Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice
Molecular and Cellular Neuroscience·2016· 14 cited
KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons
Histochemistry and Cell Biology·2016· 14 cited
Cyclin-Dependent Kinase 5 Is Involved in the Phosphorylation of Gephyrin and Clustering of GABAA Receptors at Inhibitory Synapses of Hippocampal Neurons
PLoS ONE·2014· 26 citedOpen Access
Effects of two elongation factor 1A isoforms on the formation of gephyrin clusters at inhibitory synapses in hippocampal neurons
Histochemistry and Cell Biology·2013· 26 cited
Phosphorylation of Gephyrin in Hippocampal Neurons by Cyclin-dependent Kinase CDK5 at Ser-270 Is Dependent on Collybistin
Journal of Biological Chemistry·2012· 63 citedOpen Access
Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons
Molecular and Cellular Neuroscience·2012· 28 cited
Molecular architecture of glycinergic synapses
Histochemistry and Cell Biology·2008· 21 citedOpen Access
Activity-Dependent Shedding of the NMDA Receptor Glycine Binding Site by Matrix Metalloproteinase 3: A PUTATIVE Mechanism of Postsynaptic Plasticity
PLoS ONE·2008· 44 citedOpen Access
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Frequent Co-authors

Heinrich Betz(30), Joachim Kirsch(26), Volker Schmieden(14), Bodo Laube(12), Andrea Schlicksupp(10), Stefan Kins(6), Maria Luisa Malosio(5), Alexander Kuryatov(5), Karin Gorgas(5), Éva Kiss(5), Ralph Nawrotzki(5), Cord‐Michael Becker(4), Dieter Langosch(4), Cornel Mülhardt(3), N. Rundström(3), Bertram Schmitt(3), Peter Prior(3), Claudia Kling(3), Heba Kalbouneh(3), B. Matzenbach(3)