Alexander Kuryatov

University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index5.1kcitations63works3.02yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(51), Receptor Mechanisms and Signaling(39), Ion channel regulation and function(25), Neuroscience and Neuropharmacology Research(17), Cholinesterase and Neurodegenerative Diseases(13)

Publications63 total

SR9883 is a novel small-molecule enhancer of α4β2* nicotinic acetylcholine receptor signaling that decreases intravenous nicotine self-administration in rats
Frontiers in Molecular Neuroscience·2024· 3 citedOpen Access
A new synthetic medium for the optimization of docosahexaenoic acid production in Crypthecodinium cohnii
PLoS ONE·2020· 7 citedOpen Access
Biosynthesis of uniformly carbon isotope-labeled docosahexaenoic acid in Crypthecodinium cohnii
AMB Express·2020· 4 citedOpen Access
Promoting activity of (α4)3(β2)2 nicotinic cholinergic receptors reduces ethanol consumption
Neuropsychopharmacology·2019· 10 citedOpen Access
Discovery of an intrasubunit nicotinic acetylcholine receptor–binding site for the positive allosteric modulator Br-PBTC
Journal of Biological Chemistry·2019· 10 citedOpen Access
Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models
Proceedings of the National Academy of Sciences·2017· 68 citedOpen Access
NMR SOLUTION STRUCTURE OF THE ALPHA-CONOTOXIN GID MUTANT V13Y
2017
NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID MUTANT A10V
Biological Magnetic Resonance Bank·2017Open Access
Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors
Journal of Biological Chemistry·2016· 28 citedOpen Access
A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit
Journal of Biological Chemistry·2015· 16 citedOpen Access
An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors
Journal of Biological Chemistry·2015· 41 citedOpen Access
Nicotinic receptors in non-human primates: Analysis of genetic and functional conservation with humans
Neuropharmacology·2015· 16 citedOpen Access
Expression of cloned α6* nicotinic acetylcholine receptors
Neuropharmacology·2014· 16 cited
Efficient Expression of Functional (α6β2)2β3 AChRs in Xenopus Oocytes from Free Subunits Using Slightly Modified α6 Subunits
PLoS ONE·2014· 11 citedOpen Access
Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors
PLoS ONE·2013· 51 citedOpen Access
Chemical Chaperones Exceed the Chaperone Effects of RIC-3 in Promoting Assembly of Functional α7 AChRs
PLoS ONE·2013· 28 citedOpen Access
Acetylcholine Receptor (AChR) α5 Subunit Variant Associated with Risk for Nicotine Dependence and Lung Cancer Reduces (α4β2)2α5 AChR Function
Molecular Pharmacology·2010· 165 citedOpen Access
Specific immunotherapy of experimental myasthenia gravis by a novel mechanism
Annals of Neurology·2009· 21 citedOpen Access
Mutations of cytosolic loop residues impair assembly and maturation of α7 nicotinic acetylcholine receptors
Journal of Neurochemistry·2009· 12 citedOpen Access
<i>Myasthenia Gravis and the Tops and Bottoms of AChRs</i>
Annals of the New York Academy of Sciences·2008· 32 citedOpen Access
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Frequent Co-authors

Jon Lindstrom(41), Volodymyr Gerzanich(8), Jingyi Wang(7), Mark E. Nelson(6), Felix Olale(6), Catherine H. Choi(5), Jochen Kuhse(5), Heinrich Betz(5), Theodore M. Kamenecka(5), Volker Schmieden(4), Fan Wang(3), J. Michael McIntosh(3), Sarah T. Staheli(3), Cheryl Dowell(3), James E. Garrett(3), Dieter Langosch(3), B. Matzenbach(3), Yan Zhou(2), Eliot R. Spindel(2), J. Fenimore Cooper(2)