Zhuang Hou

Shenyang Pharmaceutical University — China

Chemistry · Physical Sciences

17h-index861citations62works7.92yr avg
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Research Topics

Synthesis and Biological Evaluation(12), Antifungal resistance and susceptibility(10), Synthesis and Catalytic Reactions(10), Enzyme function and inhibition(10), Cholinesterase and Neurodegenerative Diseases(6)

Publications62 total

Vitamin B1-catalyzed intramolecular ring-opening cyclization of cyclopropanes to access benzannulated seven-membered O-heterocycles
SSRN Electronic Journal·2026Open Access
Discovery of Novel NO–Donor Containing hCA II Inhibitors with Retinal Ganglion Cell-Protective Effects for the Efficient Treatment of Glaucoma
Journal of Medicinal Chemistry·2025
Dynamic admission control and elastic reconfiguration for TSN flows under domain-controlled networks
Computer Networks·2025
CeO <sub>2</sub>-promoted spinel structural transformation enables CO <sub>2</sub> electroreduction to C <sub>2+</sub> products
Nano Research·2025Open Access
Dual‐Site Activation for Efficient Acidic CO <sub>2</sub> Electroreduction at Industrial‐Level Current Densities
Advanced Materials·2025· 13 cited
Rational Design of Rare Earth-Based Nanomaterials for Electrocatalytic Reactions
ACS Nano·2025· 7 cited
Copper-Mediated Direct Trifluoromethylation of Trichloromethyl Alkanes
Organic Letters·2025
Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance
Journal of Medicinal Chemistry·2024· 12 cited
A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression
Pharmacological Research·2024· 39 citedOpen Access
Developing Novel Coumarin-Containing Azoles Antifungal Agents by the Scaffold Merging Strategy for Treating Azole-Resistant Candidiasis
Journal of Medicinal Chemistry·2023· 25 cited
Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways
International Journal of Molecular Sciences·2023· 14 citedOpen Access
Design, synthesis, and biological evaluation of novel boron-containing azoles as potential antifungal agents
Journal of Molecular Structure·2023· 4 cited
Design, synthesis and antifungal activities of novel triazole derivatives with selenium-containing hydrophobic side chains
Bioorganic & Medicinal Chemistry Letters·2022· 13 cited
Discovery of novel selenium-containing azole derivatives as antifungal agents by exploiting the hydrophobic cleft of CYP51
European Journal of Medicinal Chemistry·2022· 23 cited
Design, Synthesis and Biological Evaluation of New Carbohydrate-Based Coumarin Derivatives as Selective Carbonic Anhydrase IX Inhibitors via “Click” Reaction
Molecules·2022· 11 citedOpen Access
Design, synthesis, and biological evaluation of selenium-containing small molecule compounds based on the dual mechanism of fungal CYP51 inhibition and fungal ROS generation
Journal of Molecular Structure·2022· 6 cited
Facile and efficient access to C1-aminosugar derivatives under mild conditions
Tetrahedron Letters·2022· 2 cited
Discovery of novel aminosaccharide-based sulfonamide derivatives as potential carbonic anhydrase II inhibitors
Bioorganic & Medicinal Chemistry Letters·2021· 1 citedOpen Access
Novel carbohydrate-based sulfonamide derivatives as selective carbonic anhydrase II inhibitors: Synthesis, biological and molecular docking analysis
Bioorganic & Medicinal Chemistry Letters·2021· 7 citedOpen Access
Discovery of 1,2,3-selenadiazole analogues as antifungal agents using a scaffold hopping approach
Bioorganic Chemistry·2021· 16 cited
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Frequent Co-authors

Chun Guo(26), Mengbi Guo(15), Hang Xu(14), Yanhua Mou(10), Ran An(10), Zhong-zuo Yan(8), Maosheng Cheng(7), Yang Liu(7), Xin Wang(7), Gaofei Wei(5), Yitong Wang(5), Yasuo Wakatsuki(5), Xin Su(4), Haonan Yu(3), Weijing Luan(3), Shanshan Cui(3), Bin Lin(3), Xinxin Zhang(3), Xiaoguang Yang(3), Rui Zhang(3)