Johnathan D. Guest

AstraZeneca (Netherlands) — Netherlands

Medicine · Health Sciences

18h-index1.2kcitations35works1.12yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(18), Hepatitis C virus research(11), SARS-CoV-2 and COVID-19 Research(8), vaccines and immunoinformatics approaches(8), Hepatitis B Virus Studies(7)

Publications35 total

Immunogenicity and efficacy of an mRNA vaccine expressing a virus-like particle spike antigen against SARS-CoV-2
npj Vaccines·2025Open Access
SARS-CoV-2 RBD Scaffolded by AP205 or TIP60 Nanoparticles and Delivered as mRNA Elicits Robust Neutralizing Antibody Responses
Vaccines·2025Open Access
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV
Structure·2025· 2 citedOpen Access
<scp>AlphaFold</scp> and Docking Approaches for Antibody–Antigen and Other Targets: Insights From <scp>CAPRI</scp> Rounds 47–55
Proteins Structure Function and Bioinformatics·2025· 3 citedOpen Access
Author response for "AlphaFold and Docking Approaches for Antibody-Antigen and Other Targets: Insights From CAPRI Rounds 47-55"
2024
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV
2024· 1 citedOpen Access
Author Correction: Molecular and phenotypic characteristics of RSV infections in infants during two nirsevimab randomized clinical trials
Nature Communications·2024· 2 citedOpen Access
Impact of <scp>AlphaFold</scp> on structure prediction of protein complexes: The <scp>CASP15‐CAPRI</scp> experiment
Proteins Structure Function and Bioinformatics·2023· 79 citedOpen Access
Molecular and phenotypic characteristics of RSV infections in infants during two nirsevimab randomized clinical trials
Nature Communications·2023· 63 citedOpen Access
Impact of AlphaFold on Structure Prediction of Protein Complexes: The CASP15-CAPRI Experiment
2023· 17 citedOpen Access
Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies
Nature Communications·2023· 31 citedOpen Access
Molecular Characterization of AZD7442 (Tixagevimab-Cilgavimab) Neutralization of SARS-CoV-2 Omicron Subvariants
Microbiology Spectrum·2023· 18 citedOpen Access
Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate
Proceedings of the National Academy of Sciences·2022· 20 citedOpen Access
Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors
Nature Communications·2022· 42 citedOpen Access
An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development
Gastroenterology·2021· 41 citedOpen Access
Structural and energetic profiling of SARS-CoV-2 receptor binding domain antibody recognition and the impact of circulating variants
PLoS Computational Biology·2021· 16 citedOpen Access
Prediction of protein assemblies, the next frontier: The <scp>CASP14‐CAPRI</scp> experiment
Proteins Structure Function and Bioinformatics·2021· 122 citedOpen Access
Structural basis for recognition of two HLA-A2-restricted SARS-CoV-2 spike epitopes by public and private T cell receptors
2021· 1 citedOpen Access
Structural basis for recognition of two HLA-A2-restricted SARS-CoV-2 spike epitopes by public and private T cell receptors
2021· 2 citedOpen Access
Author response for "Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment"
2021Open Access
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Frequent Co-authors

Brian G. Pierce(28), Rui Yin(14), Ragul Gowthaman(11), Roy A. Mariuzza(9), Zhen–Yong Keck(7), Steven K. H. Foung(7), Thomas R. Fuerst(7), Jeffrey J. Gray(6), Ruixue Wang(6), Marc F. Lensink(5), Guillaume Brysbaert(5), Paul A. Bates(5), Ren Kong(5), Hang Shi(5), Shan Chang(5), Cezary Czaplewski(5), Emilia A. Lubecka(5), Adam Liwo(5), Sheng‐You Huang(5), Luis Angel Rodríguez‐Lumbreras(5)