Pierre‐Olivier Couraud

Inserm — France

Neuroscience · Life Sciences

68h-index15.1kcitations202works0.02yr avg
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Research Topics

Barrier Structure and Function Studies(58), Drug Transport and Resistance Mechanisms(32), Cell Adhesion Molecules Research(31), Receptor Mechanisms and Signaling(17), Neuroinflammation and Neurodegeneration Mechanisms(16)

Publications202 total

The use of a multicellular <i>in vitro</i> model to investigate uptake and migration of bacterial extracellular vesicles derived from the human gut commensal <i>Bacteroides thetaiotaomicron</i>
Journal of Extracellular Biology·2023· 12 citedOpen Access
A human-derived neurovascular unit in vitro model to study the effects of cellular cross-talk and soluble factors on barrier integrity
Frontiers in Cellular Neuroscience·2022· 30 citedOpen Access
Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses
Fluids and Barriers of the CNS·2022· 36 citedOpen Access
Additional file 1 of Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses
Figshare·2022Open Access
A systemic mechanism of increased transendothelial migration of leukocytes through the blood-brain barrier in hepatic encephalopathy
Clinics and Research in Hepatology and Gastroenterology·2021· 16 citedOpen Access
Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma
Frontiers in Cell and Developmental Biology·2021· 11 citedOpen Access
High Levels of Receptor Tyrosine Kinases in CCM3-Deficient Cells Increase Their Susceptibility to Tyrosine Kinase Inhibition
Biomedicines·2020· 4 citedOpen Access
Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro
Pharmaceutics·2020· 22 citedOpen Access
Novel cyclic peptides facilitating transcellular blood-brain barrier transport of macromolecules in vitro and in vivo
Journal of Controlled Release·2020· 45 cited
Cyclocreatine Transport by SLC6A8, the Creatine Transporter, in HEK293 Cells, a Human Blood-Brain Barrier Model Cell, and CCDSs Patient-Derived Fibroblasts
Pharmaceutical Research·2020· 12 cited
Brain Endothelial Cells Release Apical and Basolateral Microparticles in Response to Inflammatory Cytokine Stimulation: Relevance to Neuroinflammatory Stress?
Frontiers in Immunology·2019· 12 citedOpen Access
Amyloid beta<sub>25‐35</sub> impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells
Journal of Neurochemistry·2019· 19 citedOpen Access
Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood–Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/ciβ
Molecular Pharmaceutics·2019· 27 cited
Cannabidiol Increases Proliferation, Migration, Tubulogenesis, and Integrity of Human Brain Endothelial Cells through TRPV2 Activation
Molecular Pharmaceutics·2019· 70 cited
Author Correction: Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
Scientific Reports·2018· 3 citedOpen Access
Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis
Scientific Reports·2018· 52 citedOpen Access
Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
Scientific Reports·2017· 91 citedOpen Access
Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function<i>In Vitro</i>
Antimicrobial Agents and Chemotherapy·2017· 34 citedOpen Access
Effect of Long-term In Vitro Lithium Exposure on mRNA Levels of Claudin-3, CYP1A1, ABCG2 and GSTM3 Genes in the hCMEC/D3 Human Brain Endothelial Cell Line
European Journal of Drug Metabolism and Pharmacokinetics·2017· 44 cited
Mechanisms underlying hPMSC‐based protection on human brain endothelial cells
The FASEB Journal·2017
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Frequent Co-authors

Ignacio A. Romero(26), Babette B. Weksler(14), John Greenwood(9), Peter Adamson(8), Babette Weksler(7), Sandrine Bourdoulous(6), Sandrine Etienne‐Manneville(4), Sylvie Cazaubon(4), A. Donny Strosberg(4), Clara Nahmias(4), Xavier Nassif(4), Anny‐Claude Luissint(3), Mélanie Di Benedetto(3), Emmanuel Eugène(3), Florence Roux‐Dalvai(2), Fabienne Glacial(2), Sandrine Dauchy(2), Richard Weaver(2), Isabelle de Waziers(2), Xavier Declèves(2)