Xavier Declèves

Délégation Paris 5 — France

Medicine · Health Sciences

45h-index6.1kcitations205works2.82yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(76), Pharmacological Effects and Toxicity Studies(38), Pharmacogenetics and Drug Metabolism(23), Barrier Structure and Function Studies(15), Forensic Toxicology and Drug Analysis(14)

Publications204 total

Correction: Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care
British Journal of Cancer·2026Open Access
Comparison of rituximab induction and maintenance regimens in anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis: PK/PD modelling of ANCA and gammaglobulin levels in real-world patients
EBioMedicine·2025Open Access
LC-MS/MS method for quantification of avacopan in human plasma from patients treated for antineutrophil cytoplasmic antibody-associated vasculitis
Journal of Pharmaceutical and Biomedical Analysis·2025Open Access
Population Pharmacokinetics of Encorafenib and Binimetinib in Real-World BRAFV600E/K-Mutant Metastatic Melanoma Patients in Comparison with Clinical Results
2025Open Access
Prediction of a <scp>CLDN18.2</scp> Targeted Antibody Drug Conjugate Pharmacokinetics in Cancer Patients Using <scp>PBPK</scp> Modeling and Simulation
CPT Pharmacometrics & Systems Pharmacology·2025· 1 citedOpen Access
Lipidomic analysis of MDCK-parental cells and MDCK-MDR1 cells exposed to GF120918 and clarithromycin highlights the role of P-glycoprotein in sphingolipid transport
Biochimie·2025Open Access
Relevance of red blood cell Lithium concentration in the management of Lithium-treated bipolar and unipolar disorders: a systematic narrative review
International Journal of Bipolar Disorders·2024· 2 citedOpen Access
Intra-individual Dose Escalation of Abiraterone According to Its Plasma Exposure in Patients with Progressive Metastatic Castration-Resistant Prostate Cancer: Results of the OPTIMABI Trial
Clinical Pharmacokinetics·2024· 3 cited
Mechanistic insights into P-glycoprotein ligand transport and inhibition revealed by enhanced molecular dynamics simulations
Computational and Structural Biotechnology Journal·2024· 9 citedOpen Access
Quantitative systems pharmacology modeling of tumor heterogeneity in response to <scp>BH3</scp>‐mimetics using virtual tumors calibrated with cell viability assays
CPT Pharmacometrics & Systems Pharmacology·2024· 1 citedOpen Access
Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR δ activation
Fluids and Barriers of the CNS·2024· 12 citedOpen Access
Extending the dosing intervals of nivolumab: model-based simulations in unselected cancer patients
British Journal of Cancer·2024· 9 citedOpen Access
Relevance of red blood cell Lithium concentration in the management of Lithium-treated bipolar and unipolar disorders: a systematic narrative review
Research Square (Research Square)·2024Open Access
Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care
British Journal of Cancer·2024· 2 citedOpen Access
A Minimal PBPK Model for Plasma and Cerebrospinal Fluid Pharmacokinetics of Trastuzumab after Intracerebroventricular Administration in Patients with HER2-Positive Brain Metastatic Localizations
Pharmaceutical Research·2023· 3 cited
Solubility of lamotrigine in age-specific biorelevant media that simulated the fasted- and fed-conditions of the gastric and intestinal environments in pediatrics and adults: implications for traditional, re-formulated, modified, and new oral formulations
BMC Biotechnology·2023· 2 citedOpen Access
Translation of Monoclonal Antibodies Pharmacokinetics from Animal to Human Using Physiologically Based Modeling in Open Systems Pharmacology (OSP) Suite: A Retrospective Analysis of Bevacizumab
Pharmaceutics·2023· 5 citedOpen Access
Toxicologie - 2e édition
HAL (Le Centre pour la Communication Scientifique Directe)·2023
Data from Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia
2023Open Access
Supplementary Data S1 from Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia
2023Open Access
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Frequent Co-authors

Jean‐Michel Scherrmann(20), Salvatore Cisternino(13), Bruno Saubaméa(8), Stéphane Mouly(8), Ramzi Shawahna(7), Salah Yousif(7), Sandrine Dauchy(6), Jean‐François Bergmann(6), Aude Jacob(5), Jean‐Michel Scherrmann(5), Célia Lloret‐Linares(5), Tetsuya Terasaki(4), Jean‐Michel Scherrmann(4), Pierre‐Olivier Couraud(4), Anne Boulay(4), Jean Laplanche(4), Nicolas Tournier(4), Christine Poitou(4), Yasuo Uchida(3), Pierre–Olivier Couraud(3)