Tim L. Tapley

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index565citations6works0.02yr avg
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Research Topics

Heat shock proteins research(5), Protein Structure and Dynamics(4), Enzyme Structure and Function(3), RNA and protein synthesis mechanisms(1), Endoplasmic Reticulum Stress and Disease(1)

Publications6 total

Genetic selection designed to stabilize proteins uncovers a chaperone called Spy
Nature Structural & Molecular Biology·2011· 172 citedOpen Access
Sequence-Dependent Peptide Binding Orientation by the Molecular Chaperone DnaK
Biochemistry·2005· 28 cited
Regulation of the HscA ATPase Reaction Cycle by the Co-chaperone HscB and the Iron-Sulfur Cluster Assembly Protein IscU
Journal of Biological Chemistry·2004· 94 citedOpen Access
Preferential Substrate Binding Orientation by the Molecular Chaperone HscA
Journal of Biological Chemistry·2004· 50 citedOpen Access
Hsc66 Substrate Specificity Is Directed toward a Discrete Region of the Iron-Sulfur Cluster Template Protein IscU
Journal of Biological Chemistry·2002· 110 citedOpen Access
The Fe/S Assembly Protein IscU Behaves as a Substrate for the Molecular Chaperone Hsc66 from Escherichia coli
Journal of Biological Chemistry·2001· 111 citedOpen Access

Frequent Co-authors

Larry E. Vickery(5), Jonathan J. Silberg(3), Kevin G. Hoff(3), Shu Quan(1), Philipp Koldewey(1), Nadine Kirsch(1), Karen M. Ruane(1), Jennifer Pfizenmaier(1), Rong Shi(1), Stephan Hofmann(1), Linda Foit(1), Guoping Ren(1), Ursula Jakob(1), Zhaohui Xu(1), Mirosław Cygler(1), James C.A. Bardwell(1), Dennis T. Ta(1), Jill R. Cupp‐Vickery(1)