Kenji Fukudome

Saga University — Japan

Medicine · Health Sciences

32h-index6.6kcitations70works0.02yr avg
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Research Topics

Blood Coagulation and Thrombosis Mechanisms(33), Immune Response and Inflammation(16), Immune Cell Function and Interaction(11), Coagulation, Bradykinin, Polyphosphates, and Angioedema(10), Vitamin K Research Studies(8)

Publications69 total

Hemostatic and protein C pathway dysfunction in the pathogenesis of experimental cerebral malaria
Haematologica·2022· 6 citedOpen Access
Hydrothermal processing of β-glucan from Aureobasidium pullulans produces a low molecular weight reagent that regulates inflammatory responses induced by TLR ligands
Biochemical and Biophysical Research Communications·2019· 10 cited
Toll-Like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
Infection and Immunity·2016· 18 citedOpen Access
Recruitment of distinct immune cell populations to the lung after intratracheal TLR4 signaling activation by two different stimulations
2016
Toll-Like Receptor 4 Agonistic Antibody Promotes Innate Immunity against Severe Pneumonia Induced by Coinfection with Influenza Virus and Streptococcus pneumoniae
Clinical and Vaccine Immunology·2013· 28 citedOpen Access
Reduced Surface Expression of TLR4 by a V254I Point Mutation Accounts for the Low Lipopolysaccharide Responder Phenotype of BALB/c B Cells
The Journal of Immunology·2012· 25 cited
Inhibition of antibody production<i>in vivo</i>by pre-stimulation of Toll-like receptor 4 before antigen priming is caused by defective B-cell priming and not impairment in antigen presentation
International Immunology·2012· 8 citedOpen Access
Multiple potential regulatory sites of TLR4 activation induced by LPS as revealed by novel inhibitory human TLR4 mAbs
International Immunology·2012· 20 citedOpen Access
Organotypic culture of human bone marrow adipose tissue
Pathology International·2010· 22 cited
Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells
International Immunology·2010· 83 cited
Blocking endothelial protein C receptor (EPCR) accelerates thrombus development in vivo
Thrombosis and Haemostasis·2010· 24 cited
Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function
The FASEB Journal·2009· 91 cited
Effect of disease activity and corticosteroids on serum levels of soluble endothelial cell protein C receptor in patients with systemic lupus erythematosus
Modern Rheumatology·2009· 5 cited
Microparticle-associated endothelial protein C receptor and the induction of cytoprotective and anti-inflammatory effects
Haematologica·2009· 90 citedOpen Access
Structure and Function of the Endothelial Cell Protein C Receptor
2009· 1 cited
Effect of disease activity and corticosteroids on serum levels of soluble endothelial cell protein C receptor in patients with systemic lupus erythematosus
Modern Rheumatology·2008· 3 cited
Preparation and Characterization of Agonistic Monoclonal Antibodies Against Toll-Like Receptor 4-MD-2 Complex
Hybridoma·2007· 19 cited
Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity
Journal of Thrombosis and Haemostasis·2007· 102 citedOpen Access
Preparation of recombinant murine tumor necrosis factor-α in Escherichia coli: A rapid method to remove tags from fusion proteins by thrombin-cleavage and ion-exchange chromatography
Protein Expression and Purification·2007· 13 cited
Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes
Annals of the Rheumatic Diseases·2007· 41 citedOpen Access
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Frequent Co-authors

Masao Kimoto(15), Naoko Tsuneyoshi(11), Osamu Yoshie(8), Shin Takagi(6), Charles T. Esmon(5), Toshio Imai(5), Hiroki Tsukamoto(5), Martina Brueckmann(5), Yorio Hinuma(4), Norio Fukuhara(4), Jun Kohara(4), Ursula Hoffmann(4), Rintaro Shimazu(3), Yoshinori Nagai(3), Kensuke Miyake(3), Deborah J. Stearns-Kurosawa(3), Shinichiro Kurosawa(3), Mikio Furuse(3), Tasuke Konno(3), Xiaofen Ye(3)