Jochen Stritzker

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index1.8kcitations47works0.02yr avg
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Research Topics

Virus-based gene therapy research(31), Cancer Research and Treatments(27), Bacteriophages and microbial interactions(9), CRISPR and Genetic Engineering(7), CAR-T cell therapy research(7)

Publications47 total

Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents
Cancer Immunology Immunotherapy·2023· 2 citedOpen Access
Keys to successful clinical translation of next-gen oncolytic virotherapies
Immuno Oncology Insights·2020
Drug-Encoded Biomarkers for Monitoring Biological Therapies
PLoS ONE·2015· 5 citedOpen Access
Doxycycline Inducible Melanogenic Vaccinia Virus as Theranostic Anti-Cancer Agent
Theranostics·2015· 20 citedOpen Access
Use of GLV-1h68 for Vaccinia Virotherapy and Monitoring
Methods in molecular biology·2015· 3 cited
Inducible Gene Expression in Tumors Colonized by Modified Oncolytic Vaccinia Virus Strains
Journal of Virology·2014· 8 citedOpen Access
Characterization of Metastasis Formation and Virotherapy in the Human C33A Cervical Cancer Model
PLoS ONE·2014· 11 citedOpen Access
PET Imaging with [<sup>68</sup>Ga]NOTA-RGD for Prostate Cancer: A Comparative Study with [<sup>18</sup>F]Fluorodeoxyglucose and [<sup>18</sup>F]Fluoroethylcholine
Current Cancer Drug Targets·2014· 17 cited
PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses
Polymer Chemistry·2013· 18 citedOpen Access
Combination of fractionated irradiation with anti‐VEGF expressing vaccinia virus therapy enhances tumor control by simultaneous radiosensitization of tumor associated endothelium
International Journal of Cancer·2013· 39 cited
Single-agent combinatorial cancer therapy
Proceedings of the National Academy of Sciences·2013· 9 citedOpen Access
Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68
Journal of Translational Medicine·2013· 66 citedOpen Access
Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer
Proceedings of the National Academy of Sciences·2013· 121 citedOpen Access
Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice
PLoS ONE·2012· 24 citedOpen Access
Preclinical Evaluation of Oncolytic Vaccinia Virus for Therapy of Canine Soft Tissue Sarcoma
PLoS ONE·2012· 56 citedOpen Access
Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy
Journal of Translational Medicine·2012· 14 citedOpen Access
Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies
Journal of Translational Medicine·2011· 14 citedOpen Access
Magnetic Resonance Imaging of Tumors Colonized with Bacterial Ferritin-Expressing Escherichia coli
PLoS ONE·2011· 46 citedOpen Access
Efficient Colonization and Therapy of Human Hepatocellular Carcinoma (HCC) Using the Oncolytic Vaccinia Virus Strain GLV-1h68
PLoS ONE·2011· 39 citedOpen Access
Prodrug converting enzyme gene delivery by -3
Figshare·2011Open Access
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Frequent Co-authors

Aladar A. Szalay(29), Werner Goebel(18), Ivaylo Gentschev(14), Sabine Pilgrim(12), Stephanie Weibel(11), Nanhai G. Chen(10), Ulrike Donat(9), Yong Yu(9), Michael Heß(8), Christoph Schoen(7), Qian Zhang(7), Philip J. Hill(5), Alexa Frentzen(5), A Szalay Aladar(5), Klaas Ehrig(4), Martin Heisig(4), Ulrike Geissinger(4), Julia Sturm(4), Barbara Härtl(4), Miriam Scadeng(3)