Alexa Frentzen

Fleet Science Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index450citations20works0.02yr avg
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Research Topics

Virus-based gene therapy research(17), Cancer Research and Treatments(12), CAR-T cell therapy research(6), Viral Infectious Diseases and Gene Expression in Insects(4), Immunotherapy and Immune Responses(3)

Publications20 total

Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis
Molecular Therapy — Oncolytics·2017· 31 citedOpen Access
Erratum to: A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer
Breast Cancer Research and Treatment·2016· 8 citedOpen Access
Drug-Encoded Biomarkers for Monitoring Biological Therapies
PLoS ONE·2015· 5 citedOpen Access
Preclinical Testing Oncolytic Vaccinia Virus Strain GLV-5b451 Expressing an Anti-VEGF Single-Chain Antibody for Canine Cancer Therapy
Viruses·2015· 41 citedOpen Access
Phase I trial of intravenous attenuated vaccinia virus (GL-ONC1) with concurrent chemoradiotherapy (CRT) for locoregionally advanced head and neck carcinoma.
Journal of Clinical Oncology·2015· 3 cited
Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy
Molecular Therapy — Oncolytics·2015· 29 citedOpen Access
Use of GLV-1h68 for Vaccinia Virotherapy and Monitoring
Methods in molecular biology·2015· 3 cited
A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer
Breast Cancer Research and Treatment·2014· 60 citedOpen Access
Evaluation of a New Recombinant Oncolytic Vaccinia Virus Strain GLV-5b451 for Feline Mammary Carcinoma Therapy
PLoS ONE·2014· 22 citedOpen Access
Combination of fractionated irradiation with anti‐VEGF expressing vaccinia virus therapy enhances tumor control by simultaneous radiosensitization of tumor associated endothelium
International Journal of Cancer·2013· 39 cited
Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer
Journal of Translational Medicine·2013· 19 citedOpen Access
Characterization and evaluation of a new oncolytic Vaccinia Virus strain LIVP6.1.1 for canine cancer therapy
Bioengineered·2012· 24 citedOpen Access
Virotherapy of Canine Tumors with Oncolytic Vaccinia Virus GLV-1h109 Expressing an Anti-VEGF Single-Chain Antibody
PLoS ONE·2012· 34 citedOpen Access
Enhanced therapeutic effects of a novel oncolytic and anti-angiogenic vaccinia virus against triple-negative breast cancer
Journal of the American College of Surgeons·2012· 2 cited
838 TWO METHODS TO IDENTIFY CLINICAL HCV ISOLATES FOR IN VITRO STUDIES
Journal of Hepatology·2012
Oncolytic Vaccinia Virus Encoding an Anti-VEGF Antibody Improves the Efficacy of Fractionated Radiation in Lung Tumor Xenografts
International Journal of Radiation Oncology*Biology*Physics·2011Open Access
Specific antibody-receptor interactions trigger InlAB-independent uptake of listeria monocytogenes into tumor cell lines
BMC Microbiology·2011· 9 citedOpen Access
Anti-VEGF single-chain antibody GLAF-1 encoded by oncolytic vaccinia virus significantly enhances antitumor therapy
Proceedings of the National Academy of Sciences·2009· 88 citedOpen Access
Listeria monocytogenes as novel carrier system for the development of live vaccines
International Journal of Medical Microbiology·2007· 33 cited
Posttranskriptionale Regulation der Internalinexpression und alternative Internalin-unabhängige Aufnahme von Listeria monocytogenes in Animalzellen
Online Publication Service of Würzburg University (Würzburg University)·2007Open Access

Frequent Co-authors

Aladar A. Szalay(14), Nanhai G. Chen(8), Yong Yu(6), Qian Zhang(6), Ivaylo Gentschev(6), Stephanie Weibel(5), Marion Adelfinger(5), Jochen Stritzker(5), Sepideh Gholami(3), Andrew A. Marano(3), Richard J. Aguilar(3), Emil Lou(3), Clarisse Eveno(3), Laurence J. Belin(3), Yuman Fong(3), Sunil J. Advani(3), Desislava Tsoneva(3), Chun-Hao Chen(2), Sho Fujisawa(2), Pat Zanzonico(2)