Michael H. Brodsky

University of Massachusetts Chan Medical School — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index6.8kcitations146works1.52yr avg
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Research Topics

CRISPR and Genetic Engineering(17), Biosensors and Analytical Detection(17), Genomics and Chromatin Dynamics(15), Salmonella and Campylobacter epidemiology(15), Listeria monocytogenes in Food Safety(13)

Publications146 total

ESC derived human cortical neurons harboring the NACC1 c.892C > T p.R298W missense mutation exhibit molecular differences from controls that influence neuronal maturation
Human Molecular Genetics·2025
Nontuberculous Mycobacterial Infection and Pulmonary Disease in Northern Israel
CHEST Journal·2024· 2 cited
Non- Tuberculous mycobacterial infection and pulmonary disease rates: a focus on M. simiae
2024
Nacc1 Mutation in Mice Models Rare Neurodevelopmental Disorder with Underlying Synaptic Dysfunction
Journal of Neuroscience·2024· 7 citedOpen Access
Contributors
Elsevier eBooks·2024
Huntingtin lowering therapeutics
Elsevier eBooks·2024
Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in <i>Sod1</i> mutant mouse model of ALS
2023· 5 citedOpen Access
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro
Nature Communications·2022· 62 citedOpen Access
CRISPR/Cas9-Mediated Excision of ALS/FTD-Causing Hexanucleotide Repeat Expansion in <i>C9ORF72</i> rescues major disease mechanisms <i>in vivo</i> and <i>in vitro</i>
2022· 1 citedOpen Access
Cell-Type-Specific Circadian Bioluminescence Rhythms in <i>Dbp</i> Reporter Mice
Journal of Biological Rhythms·2022· 10 citedOpen Access
Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities
Human Gene Therapy·2021· 14 citedOpen Access
Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila
UNC Libraries·2020Open Access
Drosophila and human RecQ5 exist in different isoforms generated by alternative splicing
UNC Libraries·2020Open Access
The alternative RPGR isoform RPGRCONST, not implicated in X-linked RP, plays a crucial role in mammalian retina.
Investigative Ophthalmology & Visual Science·2020Open Access
NeoSeekTM STEC: A Multiplex Molecular Method for Detection and Identification of Select Shiga Toxin–Producing <i>Escherichia coli</i> in Beef
Journal of AOAC International·2019· 3 citedOpen Access
Isoform-specific Rpgrmutant mice depict distinct roles of the RPGR isoforms in photoreceptors
Investigative Ophthalmology & Visual Science·2019Open Access
Independent Validation for the Polyskope 1.0 Multiplex Pathogen Detection Assay for the Detection of Shiga Toxin-Producing <i>Escherichia coli</i> Non-O157 STEC, <i>Escherichia coli</i> O157, <i>Listeria monocytogenes,</i> and <i>Salmonella</i> Species
Journal of AOAC International·2019· 1 citedOpen Access
MC-Media Pad EC for Enumeration of <i>Escherichia coli</i> and Coliforms in a Variety of Foods
Journal of AOAC International·2019· 2 citedOpen Access
MC-Media Pad CC for Enumeration of Total Coliforms in a Variety of Foods
Journal of AOAC International·2019· 2 citedOpen Access
Validation of Solus One Salmonella from Select Food Matrixes and Stainless-Steel and Plastic Environmental Surfaces
Journal of AOAC International·2019
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Frequent Co-authors

Scot A. Wolfe(13), Saurabh Sinha(8), Majid Kazemian(7), Gerald M. Rubin(5), Ryan Christensen(5), Lihua Julie Zhu(5), Gary D. Stormo(4), Metewo Selase Enuameh(4), Jeff Sekelsky(4), Sarah Oikemus(4), Hannah Pham(4), Charles Blatti(4), Garson Tsang(3), Marcus B. Noyes(3), Nadine McGinnis(3), Kent G. Golic(3), Cong Zhu(3), B W Ciebin(3), Adam Richards(3), S Celniker(3)