Steven D. Leach

Dartmouth College — United States

Medicine · Health Sciences

73h-index30.1kcitations376works0.92yr avg
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Research Topics

Pancreatic and Hepatic Oncology Research(173), Pancreatic function and diabetes(65), Cancer Genomics and Diagnostics(52), Cancer Cells and Metastasis(42), Epigenetics and DNA Methylation(29)

Publications373 total

Abstract A004: Altered RNA splicing drives pancreatic cancer by mimicking chromosome deletions
Cancer Research·2025
Adaptation and pilot implementation of a hereditary cancer risk-assessment tool for primary care
BMC Primary Care·2025Open Access
Lifetime water arsenic, genetic susceptibility, and bladder cancer in the New England Bladder Cancer Study
JNCI Cancer Spectrum·2025· 1 citedOpen Access
Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis
2025· 1 citedOpen Access
Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis
Journal of Visualized Experiments·2025Open Access
PD09-03 ZEBRAFISH AS A MODEL FOR BLADDER DEVELOPMENT TRANSCRIPTOMICS AND FUNCTION
The Journal of Urology·2025
REsolution of Symptoms afTer Oesophago-gastric cancer REsection delphi (RESTOREd)—standardizing the definition, investigation and management of gastrointestinal symptoms and conditions after surgery
British journal of surgery·2024· 3 citedOpen Access
Implementation of hereditary cancer risk assessment in primary care: Intervention strategies and proximal outcomes.
JCO Oncology Practice·2024
Abstract PR-11: Altered mRNA splicing mimics chromosome loss and drives pancreatic cancer
Cancer Research·2024
A common set of structurally distinct endogenous retroviruses predict survival in multiple human tumor types
2024Open Access
Abstract C075: Altered RNA splicing causes pancreatic cancer and exposes a therapeutic vulnerability
Cancer Research·2024
Abstract B112: Single-cell profiling of neoplastic cell populations in a KRAS-initiated zebrafish pancreatic cancer model
Cancer Research·2024
A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
Cell stem cell·2023· 61 citedOpen Access
Analysis of the distal urinary tract in larval and adult zebrafish reveals homology to the human system
Disease Models & Mechanisms·2023· 3 citedOpen Access
A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells
Journal of Molecular Cell Biology·2023· 4 citedOpen Access
Figure S4 from ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
2023Open Access
Figure S7 from ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
2023Open Access
Supplementary methods from ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
2023Open Access
Table S1 from ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
2023Open Access
Supplementary Table S3 from <i>EIF1AX</i> and <i>RAS</i> Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC
2023Open Access
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Frequent Co-authors

Anirban Maitra(11), Christine A. Iacobuzio–Donahue(10), Ralph H. Hruban(9), Elizabeth M. Jaffee(5), Michael Goggins(5), Scott E. Kern(4), Kenneth H. Yu(4), David S. Klimstra(4), Vinod P. Balachandran(4), Ingrid M. Meszoely(4), Charles J. Yeo(4), Jerry M. Rhee(4), Michael J. Parsons(4), Doris A. Stoffers(4), Olca Baştürk(3), Jennifer M. Bailey(3), Florencia McAllister(3), Gökçe Aşkan(3), Peter J. Allen(3), Pedram Argani(3)