Kerstin Schwarzwaelder

German Cancer Research Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index4.3kcitations24works0.02yr avg
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Research Topics

Virus-based gene therapy research(19), CRISPR and Genetic Engineering(11), CAR-T cell therapy research(10), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(3), RNA Interference and Gene Delivery(2)

Publications24 total

Corrigendum to “Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs”
Molecular Therapy·2011Open Access
Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy
Molecular Therapy·2011· 50 citedOpen Access
Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs
Molecular Therapy·2011· 15 citedOpen Access
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
Nature Medicine·2010· 774 citedOpen Access
National Bernstein Network Computational NeuroscienceNationales Bernstein Netzwerk Computational Neuroscience
it - Information Technology·2010Open Access
Comprehensive genomic access to vector integration in clinical gene therapy
Nature Medicine·2009· 186 cited
Detection of Retroviral Integration Sites by Linear Amplification-Mediated PCR and Tracking of Individual Integration Clones in Different Samples
Methods in molecular biology·2009· 20 cited
Comprehensive and Unbiased Integration Site Analysis in Clinical Gene Therapy.
Blood·2008
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
Journal of Clinical Investigation·2008· 1.3k citedOpen Access
Comparative integration site profile analysis in 5 clinical retroviral gene therapy studies
Blood Cells Molecules and Diseases·2008
The gene corrected clonal inventory in clinical gene therapy trials
Blood Cells Molecules and Diseases·2008
High-resolution insertion-site analysis by linear amplification–mediated PCR (LAM-PCR)
Nature Methods·2007· 331 cited
Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome.
Blood·2007· 10 cited
Phase I/II Gene Therapy Study for Chronic Granulomatous Disease: Results, Lessons and Perspectives.
Blood·2007· 3 cited
The Clonal Inventory of Gene Corrected Hematopoiesis in Three Successful Clinical Gene Therapy Trials
Blood·2007
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
Journal of Clinical Investigation·2007· 258 citedOpen Access
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
Journal of Clinical Investigation·2007· 203 citedOpen Access
Real-Time Definition of Non-Randomness in the Distribution of Genomic Events
PLoS ONE·2007· 30 citedOpen Access
Long-Term Clinical Follow-Up and Safety/Toxicity Analysis in 3 X-CGD Patients Treated by Gene Therapy and Non-Myeloablative Conditioning.
Blood·2006· 1 cited
Insertional Activation of MDS1/EVI1, PRDM16 and SETBP1 in a Successful Chronic Granulomatous Disease (CGD) Gene Therapy Trial.
Blood·2006
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Frequent Co-authors

Christof von Kalle(22), Manfred Schmidt(21), Hanno Glimm(17), Annette Deichmann(13), Adrian J. Thrasher(12), Steven J. Howe(11), Marion Ott(11), Dieter Hoelzer(11), Reinhard Seger(11), Manuel Grez(11), Stefan Stein(9), Cynthia C. Bartholomae(7), Ulrich Siler(6), Claudia R. Ball(6), Marina Cavazzana(6), Salima Hacein‐Bey‐Abina(5), Martijn H. Brugman(4), Ulrike Koehl(4), Ulrich Abel(4), Claudia Prinz(4)