Yu‐hong Lam

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Chemistry · Physical Sciences

29h-index2.8kcitations103works2.82yr avg
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Research Topics

Asymmetric Synthesis and Catalysis(28), Chemical Synthesis and Analysis(17), Fluorine in Organic Chemistry(15), Synthesis and Catalytic Reactions(15), Radical Photochemical Reactions(14)

Publications103 total

Photoredox-Mediated Alkylation of Oxime Chlorides for the Stereoselective Synthesis of Ketoximes
Organic Letters·2025
General Synthesis and Properties of Bridged, Fused, and Spirocyclic Azacycles via Intramolecular C–H Bond Amination
ACS Medicinal Chemistry Letters·2025· 1 cited
Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-19
Journal of Pharmaceutical and Biomedical Analysis·2025· 1 cited
Developing Pharmaceutically Relevant Pd-Catalyzed C–N Coupling Reactivity Models Leveraging High-Throughput Experimentation
Journal of the American Chemical Society·2025· 9 cited
Dedenser: A Python Package for Clustering and Downsampling Chemical Libraries
Journal of Chemical Information and Modeling·2025· 2 cited
Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-19
2025Open Access
A Concise Synthesis of a Key Azabicyclo[2.1.1]hexane Building Block for N-Heteroaryl Indazole LRRK2 Kinase Inhibitors
Synlett·2025· 2 cited
Highly Diastereoselective Access to Densely Functionalized Piperidine Cores of Influenza Endonuclease Inhibitors via a Metal-Free S<sub>N</sub>1 Approach
The Journal of Organic Chemistry·2025
Dedenser: a Python command line tool for clustering and downsampling chemical libraries
2024Open Access
“Build Your Own” ADC Mimics: Identification of Nontoxic Linker/Payload Mimics for HIC-Based DAR Determination, High-Throughput Optimization, and Continuous Flow Conjugation
Organic Process Research & Development·2024· 4 cited
Enantio- and Diastereoselective Total Synthesis of Belzutifan Enabled by Rh-Catalyzed Hydrogenation
Organic Letters·2024· 3 cited
“Build your own” ADC mimics: Identification of non-toxic linker/payload mimics for HIC-based DAR determination, high-throughput optimization, and continuous flow conjugation
2024· 3 citedOpen Access
Electrosynthesis of iminophosphoranes and applications in nickel catalysis
Chemical Science·2024· 11 citedOpen Access
CCDC 2205621: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2205622: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2205620: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Front Cover Picture: Copper‐Enabled Photo‐Sulfonylation of Aryl Halides Using Alkylsulfinates (Adv. Synth. Catal. 22/2023)
Advanced Synthesis & Catalysis·2023Open Access
<b>Nickel-Catalyzed Electroreductive Coupling of Alkylpyridinium Salts and Aryl Halides</b>
ACS Catalysis·2023· 30 citedOpen Access
Copper‐Enabled Photo‐Sulfonylation of Aryl Halides Using Alkylsulfinates
Advanced Synthesis & Catalysis·2023· 6 citedOpen Access
Electrosynthesis of Iminophosphoranes: Accessing P(V) Ligands from P(III) Phosphines
2023· 3 citedOpen Access
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Frequent Co-authors

K. N. Houk(21), Edward C. Sherer(6), Dan Lehnherr(6), Adam Simon(5), Véronique Gouverneur(4), Peiyuan Yu(4), Cyndi Qixin He(4), Daniel A. DiRocco(3), Charles S. Yeung(3), Erik L. Regalado(3), Mikhail Reibarkh(3), Yining Ji(3), Neil A. Strotman(3), Xiao Wang(3), Ryan D. Cohen(3), Gary E. Martin(3), Justin Jurczyk(2), Michaelyn C. Lux(2), Donovon A. Adpressa(2), Richmond Sarpong(2)