Francisco Bezanilla

University of Illinois Chicago — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

80h-index23.9kcitations420works1.12yr avg
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Research Topics

Ion channel regulation and function(243), Neuroscience and Neural Engineering(166), Cardiac electrophysiology and arrhythmias(95), Photoreceptor and optogenetics research(89), Neuroscience and Neuropharmacology Research(68)

Publications420 total

BPS2026 – Tracking the hydrophobic gate in BK channels using ANAP
Biophysical Journal·2026
BPS2026 – Mechanism of Kv channel inhibition by 4-aminopyridine, a conduction enhancing drug
Biophysical Journal·2026
BPS2026 – The closed pore and intermediate voltage sensor of the shaker potassium channel: Electromechanical coupling
Biophysical Journal·2026
Quantifying activation delay and the Cole-Moore shift via current derivatives
Biophysical Journal·2026Open Access
BPS2026 – Pore mutations in voltage-gated sodium channels stabilize the channels permanently in the slow inactivated state
Biophysical Journal·2026
Quantifying activation delay and the Cole-Moore shift via current derivatives
Biophysical Journal·2025Open Access
Molecular basis of sodium channel inactivation
Nature Communications·2025· 1 citedOpen Access
Closed state structure of the pore revealed by uncoupled Shaker K+ channel
Nature Communications·2025Open Access
Decoding electromechanical coupling in shaker potassium ion channel: Intermediate voltage sensor and close pore
Structural Dynamics·2025Open Access
Molecular Basis of Sodium Channel Inactivation
2025Open Access
Molecular Basis of Sodium Channel Inactivation
2025· 1 citedOpen Access
Closed State Structure of the Pore Revealed by Uncoupled Shaker K+ Channel
2025Open Access
Energy landscape of a Kv channel revealed by temperature steps while perturbing its electromechanical coupling
Nature Communications·2025· 3 citedOpen Access
Closed State Structure of the Pore Revealed by Uncoupled Shaker K <sup>+</sup> Channel
2025Open Access
BPS2025 - Sequential conformational changes during fast inactivation in voltage-gated sodium channels
Biophysical Journal·2025
BPS2025 - Structural basis of Shaker Kv channel gating and 4-aminopyridine binding revealed by a closed-state model
Biophysical Journal·2025
BPS2025 - A key residue in S4-S5 linker controls electromechanical coupling in Kv channels
Biophysical Journal·2025
BPS2025 - Sequential conformational changes during fast inactivation in voltage-gated sodium channels
Biophysical Journal·2025
BPS2025 - Structural basis of shaker Kv channel gating and 4-aminopyridine binding revealed by closed-state model
Biophysical Journal·2025
A sodium channel mutant removes fast inactivation with the inactivation particle bound
The Journal of General Physiology·2024· 6 citedOpen Access
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Frequent Co-authors

Enrico Stefani(8), Clay M. Armstrong(6), Baron Chanda(6), Eduardo Perozo(6), Dorine M. Starace(5), Albert Cha(4), João L. Carvalho-de-Souza(4), Rikard Blunck(4), Daniel Sigg(3), Diane M. Papazian(3), Benoı̂t Roux(3), Bozhi Tian(3), Paul R. Selvin(2), Osei Kwame Asamoah(2), Yuanwen Jiang(2), Rigo Pantoja(2), James R. Heath(2), Leslie M. Loew(2), S.A. Seoh(1), Mikhail G. Shapiro(1)