Perrine Six

Inserm — France

Chemistry · Physical Sciences

9h-index421citations18works2.52yr avg
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Research Topics

Quinazolinone synthesis and applications(6), Enzyme function and inhibition(4), PI3K/AKT/mTOR signaling in cancer(3), Biochemical and Molecular Research(3), HER2/EGFR in Cancer Research(2)

Publications18 total

Correction to “New Potent RIPK2 Inhibitors as a Promising Therapeutic Avenue for Colitis Through the Blockade of NOD Inflammatory Pathways”
Journal of Medicinal Chemistry·2024Open Access
4-Anilinoquinazoline Derivatives as the First Potent NOD1-RIPK2 Signaling Pathway Inhibitors at the Nanomolar Range
Journal of Medicinal Chemistry·2024· 2 cited
New Potent RIPK2 Inhibitors as a Promising Therapeutic Avenue for Colitis Through the Blockade of NOD Inflammatory Pathways
Journal of Medicinal Chemistry·2024· 6 cited
4-anilinoquinazoline derivatives as the first potent NOD1-RIPK2 signaling pathway inhibitors at the nanomolar range with potential anti-inflammatory activity
2024· 2 cited
One- or Two-Step Synthesis of C-8 and N-9 Substituted Purines
The Journal of Organic Chemistry·2017· 11 cited
Chiral separation of new sulfonamide derivatives and evaluation of their enantioselective affinity for human carbonic anhydrase II by microscale thermophoresis and surface plasmon resonance
Journal of Pharmaceutical and Biomedical Analysis·2017· 21 cited
Amine coupling versus biotin capture for the assessment of sulfonamide as ligands of hCA isoforms
Analytical Biochemistry·2016· 1 cited
Hemisynthesis of Anisomycin Derivatives as Antitumor Agents
Medicinal Chemistry·2015· 1 cited
Optimization of the enantioseparation of a diaryl‐pyrazole sulfonamide derivative by capillary electrophoresis in a dual <scp>CD</scp> mode using experimental design
Electrophoresis·2014· 7 cited
Inhibition of tumor cell growth and angiogenesis by 7-Aminoalkoxy-4-aryloxy-quinazoline ureas, a novel series of multi-tyrosine kinase inhibitors
European Journal of Medicinal Chemistry·2014· 34 cited
Label-free characterization of carbonic anhydrase-novel inhibitor interactions using surface plasmon resonance, isothermal titration calorimetry and fluorescence-based thermal shift assays
Journal of Molecular Recognition·2013· 24 cited
New selective carbonic anhydrase IX inhibitors: Synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides
Bioorganic & Medicinal Chemistry·2012· 62 citedOpen Access
Synthesis and Structure–Activity Relationships of (Aryloxy)quinazoline Ureas as Novel, Potent, and Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors
Journal of Medicinal Chemistry·2012· 62 citedOpen Access
ChemInform Abstract: Novel and Efficient One‐Pot Synthesis of (Aminophenyl)carbamic Acid Esters.
ChemInform·2011
Novel and Efficient One-Pot Synthesis of (Aminophenyl)carbamic Acid Esters
Synthetic Communications·2011· 5 cited
Impact of aryloxy-linked quinazolines: A novel series of selective VEGFR-2 receptor tyrosine kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2011· 75 citedOpen Access
[4-(6,7-Disubstituted quinazolin-4-ylamino)phenyl] carbamic acid esters: a novel series of dual EGFR/VEGFR-2 tyrosine kinase inhibitors
MedChemComm·2010· 62 cited
Design, Synthesis, and DNA-Binding of <i>N</i>-Alkyl(anilino)quinazoline Derivatives
Journal of Medicinal Chemistry·2010· 46 cited

Frequent Co-authors

Laurence Goossens(12), Patrick Depreux(11), Antonio Garofalo(7), Séverine Ravez(5), Tiphaine Rogez‐Florent(5), Catherine Foulon(5), Jean‐François Goossens(5), Laurent Dubuquoy(5), Régis Millet(5), Natascha Leleu‐Chavain(5), Amélie Lemoine(4), Amélie Barczyk(4), Morgane Rivoal(4), Xavier Dezitter(4), Min-Jeong Cornu-Choi(4), Amaury Farce(3), Anne‐Sophie Drucbert(3), Pierre-Marie Danzé(3), Amélie Lansiaux(2), Cécile Danel(2)