Chen‐Leng Cai

Guangzhou Institutes of Biomedicine and Health — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index8.8kcitations81works2.92yr avg
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Research Topics

Congenital heart defects research(43), Tissue Engineering and Regenerative Medicine(18), Cardiac Fibrosis and Remodeling(10), Congenital Heart Disease Studies(9), Renal and related cancers(8)

Publications81 total

In vitro generation of a ureteral organoid from pluripotent stem cells
Nature Communications·2025Open Access
Generation of a novel constitutive smooth muscle cell-specific Myh11-driven Cre mouse model
Journal of Molecular and Cellular Cardiology·2025· 5 cited
An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control
Nature Communications·2024· 8 citedOpen Access
Generation of a novel constitutive smooth muscle cell-specific <i>Myh11</i> -driven Cre mouse model
2024Open Access
Endocardial HDAC3 is required for myocardial trabeculation
Nature Communications·2024· 8 citedOpen Access
Retraction Note: REST regulates the cell cycle for cardiac development and regeneration
Nature Communications·2024Open Access
Generation of a Novel Constitutive Smooth Muscle Cell-Specific Myh11-Driven Cre Mouse Model
SSRN Electronic Journal·2024Open Access
The IncRNA, Cardiac Mesoderm Enhancer-Associated Noncoding RNA is Indispensable for Intestinal Smooth Muscle Homeostasis in Female Mice as Revealed by a Novel Endogenous Myh11-Encoded Inducible Cre Model
Gastro Hep Advances·2024· 2 citedOpen Access
Abstract 18828: Generation and Characterization of a Novel <i>Myh11</i> Knock-In Smooth Muscle Cell-Specific CreEr <sup>T2</sup> Mouse Model
Circulation·2023
Endocardial HDAC3 is required for myocardial trabeculation
2023· 2 citedOpen Access
Author Correction: Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma
Nature Communications·2023· 1 citedOpen Access
Epicardial HDAC3 Promotes Myocardial Growth Through a Novel MicroRNA Pathway
Circulation Research·2022· 36 citedOpen Access
Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase
Science·2022· 105 citedOpen Access
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact
Cardiovascular Research·2022· 55 citedOpen Access
Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma
Nature Communications·2022· 73 citedOpen Access
MiR-150 Attenuates Maladaptive Cardiac Remodeling Mediated by Long Noncoding RNA MIAT and Directly Represses Profibrotic <i>Hoxa4</i>
Circulation Heart Failure·2022· 32 citedOpen Access
Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm
Nature Communications·2021· 54 citedOpen Access
Epicardial HDAC3 promotes myocardial growth through a novel microRNA pathway
2021· 1 citedOpen Access
Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Caused by Phospholamban R14del Mutation
Circulation·2021· 28 citedOpen Access
The Role of Tbx20 in Cardiovascular Development and Function
Frontiers in Cell and Developmental Biology·2021· 50 citedOpen Access
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Frequent Co-authors

Sylvia Μ. Evans(14), Xiaoqiang Cai(11), Jianyun Yan(7), Lei Bu(6), Nishat Sultana(6), Weibin Cai(6), Ju Chen(5), Lei Yang(5), Xiaoxue Zhang(4), Mingjiang Xu(4), Roger J. Hajjar(4), Lizhu Lin(4), Feng‐Chun Yang(3), Lu Zhang(3), Dongtak Jeong(3), Bin Zhou(3), Anne Moon(3), Weinian Shou(3), Jun Hu(3), Lu Zhang(3)