Mingjiang Xu

The University of Texas Health Science Center at San Antonio — United States

Medicine · Health Sciences

45h-index8.2kcitations208works6.92yr avg
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Research Topics

Acute Myeloid Leukemia Research(90), Myeloproliferative Neoplasms: Diagnosis and Treatment(64), Epigenetics and DNA Methylation(40), Eosinophilic Disorders and Syndromes(35), Chronic Myeloid Leukemia Treatments(31)

Publications207 total

Oncogenic activation of EVC/EVC2 defines a therapeutically targetable subset of acute myeloid leukemia
Leukemia·2025
Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development
Molecular Cell·2025Open Access
5-azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia
2025Open Access
Abstract 4843: TET2 oxidizes chromatin-associated regulatory RNA m5C to potentiate anti-tumor immunity
Cancer Research·2025
Serum miR-146a and miR-155 as Predictors of Virological Control After Entecavir Withdrawal in HBeAg-Positive Chronic Hepatitis B Patients
The Turkish Journal of Gastroenterology·2025Open Access
PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1
Cell stem cell·2025· 10 citedOpen Access
HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia
Journal of Clinical Investigation·2025· 3 citedOpen Access
5-Azacytosine Induces Cytotoxicity via 5-Methylcytosine Depletion on Chromatin-Associated RNA in Leukemia
SSRN Electronic Journal·2025· 2 citedOpen Access
DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells
Nature Communications·2024· 6 citedOpen Access
<i>HoxBlinc</i> LncRNA Reprograms CTCF Independent TADs to Drive Leukemic Transcription and HSC Dysregulation in NUP98 Fusion Transformed Leukemia
Blood·2024
<i>TET2</i> Deficiency Cooperates with <i>MSH6</i> Mutation to Promote the Progression of MDS/MPN through Increasing Tumor Stem Cell Frequency
Blood·2024
RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis
Nature·2024· 62 citedOpen Access
SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis
Leukemia·2023· 10 citedOpen Access
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells
Nucleic Acids Research·2023· 14 citedOpen Access
Targeting lysine demethylase 6B ameliorates ASXL1 truncation–mediated myeloid malignancies in preclinical models
Journal of Clinical Investigation·2023· 8 citedOpen Access
P1.12-01 CD66c Activates EGFR Signalling Pathway and Promotes EMT in Lung Adenocarcinoma
Journal of Thoracic Oncology·2023Open Access
MiR-223-3p promotes genomic stability of hematopoietic progenitors after radiation
Experimental Hematology·2023Open Access
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping
EMBO Reports·2023· 20 citedOpen Access
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
Cell stem cell·2023· 96 citedOpen Access
Supplements from &lt;i&gt;IDH1/2&lt;/i&gt; Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors
2023Open Access
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Frequent Co-authors

Feng‐Chun Yang(24), Ronald Hoffman(10), Shi Chen(8), Stephen D. Nimer(7), E Bruno(6), Hongyu Ni(6), Yuan Zhou(6), Jiapeng Wang(5), Peng Jin(5), Takefumi Ishii(5), Ying Guo(5), Suming Huang(5), Feng Pan(5), Chen‐Leng Cai(4), Jianlong Wang(4), Chuan He(4), Giovanni Barosi(4), Huacheng Luo(4), Yi Qiu(4), John Mascarenhas(4)