Thomas O’Malley

Integrated BioTherapeutics (United States) — United States

Medicine · Health Sciences

13h-index751citations19works21.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Lysosomal Storage Disorders Research(12), Virus-based gene therapy research(8), Trypanosoma species research and implications(5), Adenosine and Purinergic Signaling(4), RNA Interference and Gene Delivery(3)

Publications19 total

Targeted in vivo delivery of genetic medicines utilizing an engineered lentiviral vector platform results in CAR T and NK cell generation
Molecular Therapy·2025· 21 citedOpen Access
Targeted <i>In Vivo</i> Generation of CAR T and NK Cells Utilizing an Engineered Lentiviral Vector Platform
Blood·2023· 11 cited
Urinary glycosaminoglycan concentration as a biomarker for effectiveness of enzyme replacement and gene therapy in large animal models of mucopolysaccharidoses
Molecular Genetics and Metabolism·2016
Abstract 15911: Reduced Senescence and Enhanced Proliferation of Human Cardiac Progenitor Cells Isolated and Expanded Under Reduced Oxygen Tension
Circulation·2015
Gene Therapy for Mucopolysaccharidosis Type VI Is Effective in Cats Without Pre-Existing Immunity to AAV8
Human Gene Therapy·2012· 45 citedOpen Access
Neonatal Gene Therapy With a Gamma Retroviral Vector in Mucopolysaccharidosis VI Cats
Molecular Therapy·2012· 22 citedOpen Access
Ex vivo γ-retroviral gene therapy of dogs with X-linked severe combined immunodeficiency and the development of a thymic T cell lymphoma
Veterinary Immunology and Immunopathology·2011· 8 cited
Long-term Amelioration of Feline Mucopolysaccharidosis VI After AAV-mediated Liver Gene Transfer
Molecular Therapy·2010· 72 citedOpen Access
Biochemical, Pathological, and Skeletal Improvement of Mucopolysaccharidosis VI After Gene Transfer to Liver but Not to Muscle
Molecular Therapy·2007· 70 citedOpen Access
Bone marrow transplantation for feline mucopolysaccharidosis I
Molecular Genetics and Metabolism·2007· 25 citedOpen Access
Marking of peripheral T-lymphocytes by retroviral transduction and transplantation of CD34+ cells in a canine X-linked severe combined immunodeficiency model
Veterinary Immunology and Immunopathology·2007· 6 cited
Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs
Molecular Genetics and Metabolism·2005· 41 cited
Gene Therapy Ameliorates Cardiovascular Disease in Dogs With Mucopolysaccharidosis VII
Circulation·2004· 47 citedOpen Access
Mucopolysaccharidosis type VII in a German Shepherd Dog
Journal of the American Veterinary Medical Association·2004· 32 citedOpen Access
Transplantation de moelle osseuse dans un modèle félin de mucopolysaccharidose de type I
HAL (Le Centre pour la Communication Scientifique Directe)·2004
Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs
Proceedings of the National Academy of Sciences·2002· 170 citedOpen Access
Transduction of Hepatocytes after Neonatal Delivery of a Moloney Murine Leukemia Virus Based Retroviral Vector Results in Long-Term Expression of β-Glucuronidase in Mucopolysaccharidosis VII Dogs
Molecular Therapy·2002· 59 citedOpen Access
Enzyme Replacement Therapy in Feline Mucopolysaccharidosis I
Molecular Genetics and Metabolism·2001· 90 cited
Effects of bone marrow transplantation on the cardiovascular abnormalities in canine mucopolysaccharidosis VII
Bone Marrow Transplantation·2000· 32 cited

Frequent Co-authors

Mark E. Haskins(14), Margaret A. Weil(7), N. Matthew Ellinwood(7), Katherine P. Ponder(6), Patricia A. O’Donnell(5), John R. Melniczek(4), Van W. Knox(4), Meg M. Sleeper(4), C Hasson(4), Alberto Auricchio(4), Ping Wang(4), Lingfei Xu(3), John H. Wolfe(3), Edward H. Schuchman(3), Gabriella Cotugno(3), Charles H. Vite(3), Sydney M. Evans(3), Margret L. Casal(3), Geoffrey K. Aguirre(2), Hamutal Mazrier(2)