José L. McFaline‐Figueroa

Columbia University Irving Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index6.6kcitations71works7.42yr avg
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Research Topics

Single-cell and spatial transcriptomics(28), DNA Repair Mechanisms(11), Cancer Genomics and Diagnostics(10), Glioma Diagnosis and Treatment(8), RNA Research and Splicing(8)

Publications71 total

Deep generative modeling of sample-level heterogeneity in single-cell genomics
Nature Methods·2025· 7 citedOpen Access
PT1.02.04 Mapping Gene-Environment Interactions Driving Small Cell Lung Cancer (SCLC) Initiation in Human Airway Organoids
Journal of Thoracic Oncology·2025
Multiplexed single-cell transcriptomics reveals diverse phenotypic outcomes for pathogenic SHP2 variants
2025Open Access
Spatiotemporal Single-Cell Analysis Reveals T Cell Clonal Dynamics and Phenotypic Plasticity in Human Graft-versus-Host Disease
2025· 2 citedOpen Access
Brain-wide cell-type-specific noradrenergic modulation of the transcriptome
2025Open Access
Elucidating the phenotypic landscape of neurodegeneration using multiplexed single‐cell sequencing of defined neuronal co‐cultures <i>in vitro</i>
Alzheimer s & Dementia·2024Open Access
CTNI-60. SAFETY LEAD-IN RESULTS FOR QBS10072S IN THE INDIVIDUAL SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT) TRIAL, A RANDOMIZED ADAPTIVE PLATFORM TRIAL FOR NEWLY DIAGNOSED MGMT UNMETHYLATED GLIOBLASTOMA
Neuro-Oncology·2024· 1 citedOpen Access
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells
Journal of Translational Medicine·2024· 14 citedOpen Access
Creation, Implementation, and Outcomes of a Formative Simulation Course for Promoting Healthy Equity Education in Neurology: A Pilot Study (P9-7.003)
Neurology·2024
A heterogeneous pharmaco-transcriptomic landscape induced by targeting a single oncogenic kinase
2024· 5 citedOpen Access
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor–immune hubs
Nature Biotechnology·2024· 43 citedOpen Access
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
Cell Genomics·2024· 16 citedOpen Access
High-capacity sample multiplexing for single cell chromatin accessibility profiling
BMC Genomics·2023· 3 citedOpen Access
Mitosis exit followed by death in interphase prevents the development of polyploid giant cancer cells
2023Open Access
Predicting cellular responses to complex perturbations in high‐throughput screens
Molecular Systems Biology·2023· 232 citedOpen Access
Migraine Prevalence in Gender Identity Minorities (P14-12.004)
Neurology·2023
Supplementary Figures S1-S14 from Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide
2023Open Access
Data from Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide
2023Open Access
Data from Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide
2023Open Access
Supplementary Figures S1-S14 from Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide
2023Open Access
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Frequent Co-authors

Cole Trapnell(28), Jay Shendure(15), Lauren M. Saunders(11), Peter C. Dedon(10), Jonathan S. Packer(9), Sanjay Srivatsan(9), Dana L. Jackson(9), Andrew J. Hill(8), Xiaojie Qiu(8), Riza M. Daza(7), Molly Gasperini(7), Elham Azizi(5), Hannah A. Pliner(4), Frank J. Steemers(4), Beth Martin(4), James G. Fox(4), Leona D. Samson(4), Koli Taghizadeh(4), Bo Pang(4), Lingting Shi(4)