Brendan Kenny

Newcastle University — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index6.1kcitations67works0.02yr avg
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Research Topics

Escherichia coli research studies(52), Bacterial Genetics and Biotechnology(30), Viral gastroenteritis research and epidemiology(21), Probiotics and Fermented Foods(20), Antibiotic Resistance in Bacteria(10)

Publications67 total

Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment
Scientific Reports·2015· 7 citedOpen Access
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic<i>Escherichia coli</i>Tir effector
Cell Adhesion & Migration·2014· 16 citedOpen Access
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic <i>Escherichia coli</i> Tir effector
Figshare·2014Open Access
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic <i>Escherichia coli</i> Tir effector
Figshare·2014Open Access
Do Caco-2 Subclones Provide More Appropriate <i>in Vitro</i> Models for Understanding how Human Enteric Pathogens Cause Disease?
Future Microbiology·2013· 1 cited
Insights into the Pathogenesis of Enteropathogenic E. coli Using an Improved Intestinal Enterocyte Model
PLoS ONE·2013· 20 citedOpen Access
A bacterial encoded protein induces extreme multinucleation and cell-cell internalization in intestinal cells
Tissue Barriers·2013· 9 citedOpen Access
The Enteropathogenic E. coli (EPEC) Tir Effector Inhibits NF-κB Activity by Targeting TNFα Receptor-Associated Factors
PLoS Pathogens·2011· 61 citedOpen Access
Cell-surface nucleolin is sequestered into EPEC microcolonies and may play a role during infection
Microbiology·2011· 11 citedOpen Access
Why and how enteropathogenic E.coli (EPEC) inhibit innate immune response pathways of enterocytes
Frontiers in Immunology·2011Open Access
Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of Pathogenic Escherichia coli
Journal of Biological Chemistry·2010· 78 citedOpen Access
The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction
PLoS Pathogens·2010· 64 citedOpen Access
The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector
Cellular Microbiology·2010· 30 citedOpen Access
PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463
Gut Microbes·2010· 8 citedOpen Access
Dual infection system identifies a crucial role for PKA-mediated serine phosphorylation of the EPEC-Tir-injected effector protein in regulating Rac1 function
Cellular Microbiology·2009· 17 cited
Host–microbe interactions: bacteria
Current Opinion in Microbiology·2009· 46 cited
The effector repertoire of enteropathogenic E. coli: ganging up on the host cell
Current Opinion in Microbiology·2009· 214 citedOpen Access
Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic <i>Escherichia coli</i> O127:H6 Strain E2348/69
Journal of Bacteriology·2008· 336 citedOpen Access
Dual infection of mammalian cells provides novel insights into injected bacterial effector protein function
International Journal of Medical Microbiology·2008
Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function
Cellular Microbiology·2007· 91 citedOpen Access
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Frequent Co-authors

Paul Dean(12), B. Brett Finlay(8), I. Barry Holland(8), Markus Stein(5), Marc Maresca(5), Sabine Quitard(5), Mark A. Jepson(4), Jonathan M. Warawa(4), Gad Frankel(3), Alan D. Leard(3), Marie‐Hélène Ruchaud‐Sparagano(3), Sabrina Mühlen(3), Akira ABE(2), Xiangyi Gan(2), Stephanie Schüller(2), Alan D. Phillips(2), Richard Haigh(2), Mark A. Blight(2), I.B. Holland(2), Christian Chervaux(2)