Thomas B. Huffaker

University of Utah — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index925citations18works0.02yr avg
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Research Topics

MicroRNA in disease regulation(8), Extracellular vesicles in disease(5), Circular RNAs in diseases(5), Cancer Immunotherapy and Biomarkers(4), Immune Cell Function and Interaction(4)

Publications18 total

MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation
The Journal of Immunology·2023· 12 citedOpen Access
Cell-specific roles for miR-155 during neuroinflammation
The Journal of Immunology·2022
A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages
Nature Communications·2021· 61 citedOpen Access
Aging impairs mouse skeletal muscle macrophage polarization and muscle-specific abundance during recovery from disuse
American Journal of Physiology-Endocrinology and Metabolism·2019· 70 citedOpen Access
MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers
JCI Insight·2019· 51 citedOpen Access
Single cell sequencing reveals regulatory role for T cell expressed microRNA-155 within the tumor microenvironment.
The Journal of Immunology·2018
004 T cell specific microRNA-155 regulates the immune landscape of B16f10 melanoma
Journal of Investigative Dermatology·2018
Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli
The Journal of Immunology·2017· 90 citedOpen Access
Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade
Journal of Biological Chemistry·2017· 84 citedOpen Access
miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response
Blood·2017· 66 citedOpen Access
MicroRNA 155 and viral-induced neuroinflammation
Journal of Neuroimmunology·2017· 39 citedOpen Access
MiR-155 Promotes FLT3-ITD-Induced Myeloproliferative Disease through Inhibition of Interferon Signaling
Blood·2016· 1 cited
Genome-Wide Crispr-Cas9 Screen Identifies Functionally Relevant Micro-RNAs in FLT3-ITD+ AML
Blood·2015
miR-155-SOCS1 as a Functional Axis: Satisfying the Burden of Proof
Immunity·2015· 36 citedOpen Access
miR-155 Promotes T Follicular Helper Cell Accumulation during Chronic, Low-Grade Inflammation
Immunity·2014· 154 citedOpen Access
MicroRNAs, T follicular helper cells, and inflammatory status during aging (IRM6P.714)
The Journal of Immunology·2014
MicroRNA-155 Confers Encephalogenic Potential to Th17 Cells by Promoting Effector Gene Expression
The Journal of Immunology·2013· 92 cited
Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity
Cell Reports·2012· 170 citedOpen Access

Frequent Co-authors

Ryan M. O’Connell(18), June L. Round(12), Ruozhen Hu(10), Marah C. Runtsch(10), Margaret Alexander(7), Dominique Kagele(6), Dinesh S. Rao(5), Jared Wallace(5), Erin Bake(4), Andrew G. Ramstead(4), Timothy L. Mosbruger(4), Matthew A. Williams(3), Kaylyn M. Bauer(3), Soh-Hyun Lee(3), William W. Tang(3), Jacob Thompson(3), Warren P. Voth(3), Rodney R. Miles(3), H. Atakan Ekiz(3), Wei Su(2)