Yingzheng Xu

University of Minnesota — United States

Immunology and Microbiology · Life Sciences

10h-index458citations49works8.12yr avg
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Research Topics

Immune cells in cancer(22), Ferroptosis and cancer prognosis(12), RNA modifications and cancer(10), Cancer, Lipids, and Metabolism(10), Epigenetics and DNA Methylation(8)

Publications49 total

Immunotherapy promotes tumor adapted TNF-producing neutrophils that impair T cell clonal expansion and resident memory formation in pancreatic ductal adenocarcinoma 2236
The Journal of Immunology·2025Open Access
Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner
Journal of Leukocyte Biology·2025Open Access
Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages
Communications Biology·2025· 10 citedOpen Access
CD44 in myEloid cells is a major driver of liver inflammation and injury in alcohol-related liver disease
Hepatology·2025· 1 citedOpen Access
Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages (LAMs)
2024· 3 citedOpen Access
Loss of TREM2 diminishes CAA despite an overall increase of amyloid load in Tg‐SwDI mice
Alzheimer s & Dementia·2024· 10 citedOpen Access
Adrenal gland macrophages regulate glucocorticoid production through Trem2 and TGF-β
JCI Insight·2024· 12 citedOpen Access
Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability—Brief Report
Arteriosclerosis Thrombosis and Vascular Biology·2024· 45 citedOpen Access
Abstract 133: Trem2 Agonist Promotes Atherosclerotic Plaque Stability
Arteriosclerosis Thrombosis and Vascular Biology·2024
Abstract 2051: Monocyte Recruitment And Fate Specification Within Atherosclerotic Lesions
Arteriosclerosis Thrombosis and Vascular Biology·2024
Loss of TREM2 exacerbates parenchymal amyloid pathology but diminishes CAA in Tg-SwDI mice
2023· 1 citedOpen Access
Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis
Nature Cardiovascular Research·2023· 128 citedOpen Access
Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability
2023· 6 citedOpen Access
Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma
Cell Reports·2023· 46 citedOpen Access
Abstract 146: Foamy Macrophages Rely On Trem2 For Survival During Atherosclerosis
Arteriosclerosis Thrombosis and Vascular Biology·2023· 1 cited
Supplementary Table S1 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
2023Open Access
Data from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
2023Open Access
Supplementary Dataset 2 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
2023Open Access
Figure S3 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
2023Open Access
Figure S2 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
2023Open Access
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Frequent Co-authors

Jesse W. Williams(46), Danielle N. Huggins(25), Rebecca S. LaRue(25), Ying Wang(25), Todd P. Knutson(25), Kathryn L. Schwertfeger(25), Patricia R. Schrank(16), Michael T. Patterson(12), Ainsley E. Kennedy(11), Konstantin Zaitsev(10), Hannah Hillman(9), Alisha Zhu(9), Ingunn M. Stromnes(9), Maria Firulyova(8), Xavier S. Revelo(5), Stoyan Ivanov(5), Tyler D. Bold(5), Adam L. Burrack(5), Zoe C. Schmiechen(5), Ebony A. Miller(5)