Ingunn M. Stromnes

University of Minnesota — United States

Medicine · Health Sciences

32h-index5.8kcitations135works2.22yr avg
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Research Topics

CAR-T cell therapy research(78), Cancer Immunotherapy and Biomarkers(52), Immune Cell Function and Interaction(39), Immunotherapy and Immune Responses(32), Pancreatic and Hepatic Oncology Research(24)

Publications135 total

Functional genomics for improving adoptive T-cell transfer therapies
Journal for ImmunoTherapy of Cancer·2025Open Access
IL-15 complex enhances therapeutic efficacy of anti-PD-L1 in a T cell–dependent and NK cell–independent manner in a murine model of pancreatic ductal adenocarcinoma
The Journal of Immunology·2025Open Access
Immunotherapy promotes CD4 T cell effector function, limits Tregs, and relies on CD4 T cells to restrain excessive myeloid infiltration in a preclinical model of pancreatic cancer 2394
The Journal of Immunology·2025Open Access
T cell receptor binding strength dictates CD8+ T cell function in pancreatic cancer 2855
The Journal of Immunology·2025Open Access
IL-15 complex with agonistic anti-CD40 + anti-PDL1 overcomes T cell exhaustion and drives a T-bet+ effector program for pancreatic ductal adenocarcinoma eradication 3573
The Journal of Immunology·2025Open Access
αβTCR targeting to Trac can bypass β-selection via transient γδTCR expression 2721
The Journal of Immunology·2025Open Access
Immunotherapy promotes tumor adapted TNF-producing neutrophils that impair T cell clonal expansion and resident memory formation in pancreatic ductal adenocarcinoma 2236
The Journal of Immunology·2025Open Access
Targeting Regulatory T cells controls metastatic pancreatic ductal adenocarcinoma by modulation of conventional CD4 T helper cells 3557
The Journal of Immunology·2025Open Access
<i>Sleeping Beauty</i> mutagenesis identifies <i>BACH2</i> and other regulators of CD8 <sup>+</sup> T cell exhaustion, persistence <i>in vivo</i> , and CAR-T function under tumor-associated chronic antigen stimulation
2025· 1 citedOpen Access
Beyond the native repertoire
Science·2025· 1 cited
Maturation of thymocytes with a monoclonal TCR under control of <i>Trac</i> promoter elements in the absence of β-selection
ImmunoHorizons·2025· 2 citedOpen Access
Abrogating TGFβ signaling in TCR-engineered T cells and enhancing antigen processing by tumor cells promotes sustained therapeutic activity in pancreatic ductal adenocarcinoma
2025· 1 citedOpen Access
Supplementary Figure 6 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
Supplementary Figure 1 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
Data from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025· 1 citedOpen Access
Supplementary Tables from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
Supplementary Figure 3 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
Supplementary Figure 7 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
Supplementary Figure 2 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
Supplementary Figure 9 from IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8&lt;sup&gt;+&lt;/sup&gt; T cells Infiltrating Pancreatic Ductal Adenocarcinoma
2025Open Access
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Frequent Co-authors

Philip D. Greenberg(17), Adam L. Burrack(12), Sunil R. Hingorani(9), Zoe C. Schmiechen(8), Karin E. Peterson(7), Kim J. Hasenkrug(7), Ellen J. Spartz(7), Meagan R. Rollins(7), Joan Goverman(6), Michael T. Patterson(6), Eduardo Cruz-Hinojoza(6), Ebony A. Miller(6), Ronald J. Messer(5), Thomas M. Schmitt(5), Ayaka Hulbert(5), Yingzheng Xu(5), Grant H. Hickok(5), Patricia R. Schrank(5), Ainsley E. Kennedy(5), Jesse W. Williams(5)