Brent L. Podlogar

Bayer (United States) — United States

Computer Science · Physical Sciences

11h-index409citations23works0.02yr avg
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Research Topics

Computational Drug Discovery Methods(4), Chemical Synthesis and Analysis(3), Cancer therapeutics and mechanisms(3), Protein Structure and Dynamics(2), HIV Research and Treatment(2)

Publications23 total

Constrained analogs of CB-1 antagonists: 1,5,6,7-Tetrahydro-4H-pyrrolo[3,2-c]pyridine-4-one derivatives
Bioorganic & Medicinal Chemistry Letters·2006· 26 citedOpen Access
Patents on tetracycline and tetracycline derivatives as antimicrobials: January 1998 – October 2002
Expert Opinion on Therapeutic Patents·2003· 3 cited
Patents on tetracycline and tetracycline derivatives as antimicrobials: January 1998 ? October 2002
Expert Opinion on Therapeutic Patents·2003
3D-Quantitative Structure Activity Relationships of Biphenyl Carboxylic Acid MMP-3 Inhibitors: Exploring Automated Docking as Alignment Method
Quantitative Structure-Activity Relationships·2001
3D-Quantitative Structure Activity Relationships of Biphenyl Carboxylic Acid MMP-3 Inhibitors: Exploring Automated Docking as Alignment Method
Quantitative Structure-Activity Relationships·2001· 18 cited
“Holistic” In Silico Methods to Estimate the Systemic and CNS Bioavail-abilities of Potential Chemotherapeutic Agents
Current Topics in Medicinal Chemistry·2001· 17 cited
QSAR and CoMFA: a perspective on the practical application to drug discovery.
PubMed·2000· 56 cited
Synthesis and evaluation of 4-(N,N-diarylamino)piperidines with high selectivity to the delta-opioid receptor: a combined 3D-QSAR and ligand docking study.
PubMed·2000· 11 cited
Conformational analysis of the endogenous μ‐opioid agonist endomorphin‐1 using NMR spectroscopy and molecular modeling
FEBS Letters·1998· 74 citedOpen Access
Synthesis and Inhibitory Activity of Novel Tri- and Tetracyclic Quinolines against Topoisomerases
Bioorganic & Medicinal Chemistry·1998· 48 cited
Protein Structure Determination Using A Combination of Comparative Modeling and NMR Spectroscopy. Application to the Response Regulator Protein, Spo0F
Journal of Medicinal Chemistry·1997· 2 cited
DNA Gyrase Inhibitory and Antimicrobial Activities of Some Diphenic Acid Monohydroxamides
Journal of Medicinal Chemistry·1997· 19 citedOpen Access
NMR three‐dimensional solution structure of the serine protease inhibitor cyclotheonamide A
Biopolymers·1997
NMR three-dimensional solution structure of the serine protease inhibitor cyclotheonamide A
Biopolymers·1997· 5 cited
Elucidation of the Mechanism of Inhibition of Human Immunodeficiency Virus 1 Protease by Difluorostatones
ACS symposium series·1996
Design, Synthesis, and Conformational Analysis of a Novel Macrocyclic HIV-Protease Inhibitor
Journal of Medicinal Chemistry·1994· 31 citedOpen Access
ChemInform Abstract: Synthesis of Chiral Hydroxylated Quinolizidines via Vinylogous Bischler‐Napieralski Nitrilium Ion Cyclizations.
ChemInform·1994
Synthesis of Chiral Hydroxylated Quinolizidines via Vinylogous Bischler-Napieralski Nitrilium Ion Cyclizations
The Journal of Organic Chemistry·1994· 25 cited
Molecular mechanics calculations of epoxides. Extension of the MM2 force field
The Journal of Organic Chemistry·1989· 22 cited
ChemInform Abstract: A Conformational Criterion for Aromaticity and Antiaromaticity.
ChemInform·1988
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Frequent Co-authors

John F. Barrett(5), Douglas J. Raber(5), Gregory C. Leo(4), David A. Demeter(4), Kwasi A. Ohemeng(4), David M. Ferguson(3), Edward W. Huber(3), Ingo Muegge(3), Patricia A. McDonnell(3), Gary W. Caldwell(3), Allen B. Reitz(2), Van N. Nguyen(2), William A. Glauser(2), Walter R. Rodriguez(2), Robert A. Farr(2), Céline Tarnus(2), Daniel Schirlin(2), Angela L. Marquart(2), Norton P. Peet(2), Herschel J. R. Weintraub(2)