Ioannis I. Verginadis

University of Pennsylvania — United States

Medicine · Health Sciences

30h-index3.6kcitations201works5.02yr avg
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Research Topics

Effects of Radiation Exposure(48), Head and Neck Cancer Studies(31), Radiation Therapy and Dosimetry(23), Salivary Gland Disorders and Functions(21), Oral health in cancer treatment(19)

Publications201 total

Abstract A103: Targeting STAT3 in cancer-associated fibroblasts reprograms the stroma and enhances CD8+ T cell-mediated immunity in PDAC
Cancer Research·2025
FLASH PROTON RADIATION REDUCES OCULAR TOXICITY AND PRESERVES VISION BY MINIMIZING CORNEAL CELL DEATH IN A PRECLINICAL MODEL
Radiotherapy and Oncology·2025
Development of Computational Immunohistochemical Stained Tissue Analysis to Quantitatively Investigate Intracellular Radiochemical Oxygen Depletion in FLASH Irradiated Murine Intestine
International Journal of Radiation Oncology*Biology*Physics·2025
Physicochemical indication of the FLASH effect from shoot-through proton pencil beam scanning parameters delivered under ultra-high dose rates
Physics in Medicine and Biology·2025Open Access
4232 Physicochemical Indication of the FLASH Effect from Shoot-through Proton Pencil Beam Scanning Parameters Delivered under Ultra-high Dose Rates
Radiotherapy and Oncology·2025
The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers
Communications Medicine·2025· 7 citedOpen Access
FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone
Radiotherapy and Oncology·2025· 19 citedOpen Access
Radiotherapy toxicities: mechanisms, management, and future directions
The Lancet·2025· 57 citedOpen Access
788 Enhancing chimeric antigen receptor T Cell therapy with precision proton radiotherapy
Regular and Young Investigator Award Abstracts·2024Open Access
NIMG-60. SUBTYPING GLIOBLASTOMA FROM JOINT CLUSTERING OF IMAGING AND GENOMIC DATA
Neuro-Oncology·2024Open Access
Brown adipose tissue thermogenesis rhythms are driven by the SCN independent of adipocyte clocks
2024Open Access
FLASH Proton Radiotherapy on a Model of Radiation-Induced Myocardial Fibrosis
International Journal of Radiation Oncology*Biology*Physics·2024
Combining Proton Radiation Therapy and Mesothelin-Targeting Chimeric Antigen Receptor T-cell Therapy to Improve Outcomes in Pancreatic Cancer
International Journal of Radiation Oncology*Biology*Physics·2024
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies
Science Translational Medicine·2024· 11 citedOpen Access
Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy
2024· 11 citedOpen Access
Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer
Proceedings of the National Academy of Sciences·2024· 15 citedOpen Access
FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone
2024· 5 citedOpen Access
Supplementary Table 1 from Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer
2024Open Access
Figure S4 from Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer
2024Open Access
Figure S5 from Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer
2024Open Access
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Frequent Co-authors

Constantinos Koumenis(26), Angelos Evangelou(13), Anastasia Velalopoulou(12), Yannis V. Simos(12), Spyridon Karkabounas(10), Michele M. Kim(8), Eric S. Diffenderfer(7), Khayrullo Shoniyozov(7), James M. Metz(7), Alexandros Charalabopoulos(7), Keith A. Cengel(6), S.K. Hadjikakou(6), Denisa Goia(5), Mary Putt(5), Amit Maity(5), Theresa M. Busch(5), Lei Dong(5), Serge Y. Fuchs(5), J. Alan Diehl(5), Enrico Radaelli(5)