Constantinos Koumenis

University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

66h-index21.7kcitations515works3.52yr avg
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Research Topics

Endoplasmic Reticulum Stress and Disease(96), Autophagy in Disease and Therapy(77), Cancer, Hypoxia, and Metabolism(74), Effects of Radiation Exposure(58), Cancer Immunotherapy and Biomarkers(48)

Publications513 total

Development and Evaluation of a Proton Irradiation Setup for Radiobiological Studies Using Low-Energy Protons with a Polyenergetic Spectrum (0–5.5 MeV, Mean 4.1 MeV)
Radiation·2026Open Access
Deliverable proton conformal FLASH radiotherapy treatment planning for head and neck re-irradiation patients
Radiotherapy and Oncology·2025
Supplementary Table 1 - Gene Expression from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supp. Figure 6 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supp. Figure 4 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supp. Figure 3 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supp. Figure 5 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supp. Figure 1 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supplementary Figure Legends from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
Supp. Figure 2 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance
2025Open Access
1337 Gut-targeted antibiotic modulation enhances radiotherapy in NSCLC: New epigenetic and dendritic cell functional correlates from a randomized pilot trial
2025Open Access
Tumor Associated Mitochondria Antigens (TAMAs) vaccine is effective on tumor and tumor associated endothelial cells: from the mechanisms to the clinical validation 3298
The Journal of Immunology·2025Open Access
Abstract A101: Targeting ATF4 reshapes PDAC’s tumor microenvironment to enhance CAR T-cell anti-tumor efficacy
Cancer Research·2025
Comparative metabolomic analysis of human lung slices (hu-PCLS) exposed to either standard or FLASH protons: a pilot study
Radiation Oncology·2025· 2 citedOpen Access
FLASH PROTON RADIATION REDUCES OCULAR TOXICITY AND PRESERVES VISION BY MINIMIZING CORNEAL CELL DEATH IN A PRECLINICAL MODEL
Radiotherapy and Oncology·2025
Physicochemical indication of the FLASH effect from shoot-through proton pencil beam scanning parameters delivered under ultra-high dose rates
Physics in Medicine and Biology·2025Open Access
Enhancing outcomes in medically inoperable early-stage NSCLC with gut-targeted antibiotics and stereotactic body radiotherapy: results from a randomized pilot study
Journal for ImmunoTherapy of Cancer·2025· 4 citedOpen Access
4232 Physicochemical Indication of the FLASH Effect from Shoot-through Proton Pencil Beam Scanning Parameters Delivered under Ultra-high Dose Rates
Radiotherapy and Oncology·2025
Abstract 1334: FLASH proton radiotherapy mitigates corneal damage and stimulates wound healing in mice
Cancer Research·2025
The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers
Communications Medicine·2025· 7 citedOpen Access
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Frequent Co-authors

J. Alan Diehl(11), Serge Y. Fuchs(11), Ioannis I. Verginadis(9), Jiangbin Ye(8), Feven Tameire(7), Bradly G. Wouters(6), Diane Fels(5), Amit Maity(5), Marianne Koritzinsky(4), David Ron(4), Xiaowei Xu(4), Ravi K. Amaravadi(4), Keith A. Cengel(4), Davide Ruggero(4), Amato J. Giaccia(4), Nektaria Maria Leli(4), Stephen W. Tuttle(4), Lin Zhang(4), Menggui Huang(4), Duo Zhang(4)