David Ron

AstraZeneca (United Kingdom) — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

130h-index95.3kcitations420works2.32yr avg
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Research Topics

Endoplasmic Reticulum Stress and Disease(244), RNA regulation and disease(90), Autophagy in Disease and Therapy(68), RNA Research and Splicing(43), Pancreatic function and diabetes(43)

Publications418 total

Mediastinal myeloid sarcoma
Blood·2025
Bilateral optic nerve infiltration in pediatric ACUTE promyelocytic leukemia: A RARE and aggressive CNS relapse with probable ATRA resistance
Blood·2025Open Access
A structural basis for chaperone repression of stress signaling from the endoplasmic reticulum
Molecular Cell·2025· 1 citedOpen Access
A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response
2025· 1 citedOpen Access
Translon: a single term for translated regions
Nature Methods·2025· 7 citedOpen Access
Metabolite import via SLC33A1 enables ATF6 activation by endoplasmic reticulum stress
2025· 1 citedOpen Access
eLife Assessment: Cardiolipin deficiency disrupts electron transport chain to drive steatohepatitis
2025Open Access
A structural basis for chaperone repression of stress signalling from the endoplasmic reticulum
2025Open Access
Protocol for iterative enrichment of integrated sgRNAs via derivative CRISPR-Cas9 libraries from genomic DNA of sorted fixed cells
STAR Protocols·2024Open Access
eLife assessment: An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression
2024Open Access
Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatases
Proceedings of the National Academy of Sciences·2024· 5 citedOpen Access
eLife Assessment: An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression
2024Open Access
Author response: A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
2024Open Access
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
eLife·2024Open Access
A genome wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
2024Open Access
Author response: A genome wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
2024Open Access
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
eLife·2024· 10 citedOpen Access
A genome wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6⍺
2024Open Access
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response
Proceedings of the National Academy of Sciences·2024· 5 citedOpen Access
A genome wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
2024Open Access
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Frequent Co-authors

Heather P. Harding(28), Yuhong Zhang(10), Isabel Novoa(6), Huiqing Zeng(6), Fumihiko Urano(4), Anne Bertolotti(4), Donalyn Scheuner(4), Randal J. Kaufman(4), Phoebe D. Lu(3), Marcella A. Calfon(3), Chi Young Yun(3), Ira Tabas(3), Stefan J. Marciniak(3), Cole M. Haynes(3), Peter Walter(2), John C. Bell(2), Ronald C. Wek(2), Xiao-Zhong Wang(2), Peter Chung(2), Linda M. Hendershot(2)