John C. Bell

University of Ottawa — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

84h-index30.4kcitations451works4.32yr avg
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Research Topics

Virus-based gene therapy research(281), CAR-T cell therapy research(132), Cancer Research and Treatments(83), Viral Infectious Diseases and Gene Expression in Insects(76), Animal Virus Infections Studies(50)

Publications451 total

A Universal Boosting Strategy for Adoptive T-cell Therapy Using a Paired Vaccine/Chimeric Antigen Receptor
Cancer Immunology Research·2025
Effect of extracellular vesicles in remodeling the tumor microenvironment by DNMT1 downregulation for enhanced cancer immunotherapy
Journal for ImmunoTherapy of Cancer·2025Open Access
Oncolytic Maraba virus MG1 mediates direct and natural killer cell-dependent lysis of Ewing sarcoma
2025Open Access
RNAi Screening in Tumor Cells Identifies Artificial microRNAs That Improve Oncolytic Virus Replication
Pharmaceuticals·2025Open Access
Corrigendum: Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment
Frontiers in Immunology·2025Open Access
Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment
Frontiers in Immunology·2024· 5 citedOpen Access
Antibiotic-mediated selection of randomly mutagenized and cytokine-expressing oncolytic viruses
Nature Biomedical Engineering·2024· 5 cited
The potential clinical utility of Whole Genome Sequencing for patients with cancer: evaluation of a regional implementation of the 100,000 Genomes Project
British Journal of Cancer·2024· 9 citedOpen Access
Fast parallel index-based GPU particle collision detection for science and engineering.
2024Open Access
PR070/#754  The potential clinical utility of whole genome sequencing for patients with gynaecological cancer: the 100,000 genomes project regional implementation
2024
1204P Real-world utility of whole genome sequencing for patients with cancer: Evaluation of a regional implementation of the 100,000 genomes project
Annals of Oncology·2024
Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy
Nature Communications·2024· 12 citedOpen Access
Molecular Characterization and Xenotransplantation of Pancreatic Cancer Using Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA)
Cancers·2024· 1 citedOpen Access
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling
Journal for ImmunoTherapy of Cancer·2024· 10 citedOpen Access
PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway
The Journal of Experimental Medicine·2024· 9 citedOpen Access
Enhancing oncolytic virotherapy by exosome-mediated microRNA reprograming of the tumour microenvironment
2024· 2 citedOpen Access
Tutorial: design, production and testing of oncolytic viruses for cancer immunotherapy
Nature Protocols·2024· 33 cited
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T cell receptor signalling
2024Open Access
Optimizing oncolytic virus design: a “Swiss army knife” approach to create a systemically delivered therapeutic
Signal Transduction and Targeted Therapy·2024· 1 citedOpen Access
Abstract B054: Defective STING signaling in low-grade serous ovarian cancer: an opportunity for oncolytic viruses therapy
Cancer Research·2024
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Frequent Co-authors

David F. Stojdl(16), David H. Kirn(16), Caroline J. Breitbach(14), Theresa Falls(11), Brian D. Lichty(10), Kelley A. Parato(9), Harold Atkins(8), Anne Moon(8), Manijeh Daneshmand(8), Tae-Ho Hwang(8), Jean‐Simon Diallo(7), Ricardo Marius(5), James M. Burke(5), Heather P. Harding(4), David Ron(4), Jennifer M Paterson(4), Shane Knowles(4), Nahum Sonenberg(4), Peter I. Duncan(4), Fabrice Le Bœuf(4)