Sanjay D. Khare

Best Biotech — United States

Medicine · Health Sciences

17h-index2.7kcitations37works12.52yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(14), T-cell and B-cell Immunology(8), Spondyloarthritis Studies and Treatments(8), Lymphoma Diagnosis and Treatment(7), Rheumatoid Arthritis Research and Therapies(6)

Publications37 total

Discovery of Biologics as Therapeutic Drugs: Past, Present, and Future
2025
Toripalimab, a therapeutic monoclonal anti-PD-1 antibody with high binding affinity to PD-1 and enhanced potency to activate human T cells
Cancer Immunology Immunotherapy·2024· 25 citedOpen Access
Abstract C069: Toripalimab an anti-PD-1 antibody that demonstrates potent T cell activation and enhanced clinical efficacy irrespective of PD-L1 status
Molecular Cancer Therapeutics·2023
468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activation and enhanced clinical efficacy irrespective of PD-L-1 status
Regular and Young Investigator Award Abstracts·2023· 1 citedOpen Access
Abstract B182: IGN004 is an antibody-interferon-alpha fusion protein against a novel tumor-associated antigen with both direct anti-tumor and immunostimulatory effects
Cancer Immunology Research·2016
Antibody-Interferon-Alpha Fusion Protein Therapy for the Treatment of B-Cell Non-Hodgkin Lymphoma: Enhanced ADCC, Inhibition of Proliferation, and In Vivo Eradication of CD20+ Human Lymphomas
Blood·2015· 3 citedOpen Access
IGN004 is an antibody-interferon-alpha fusion protein against a novel tumor-associated antigen with both direct anti-tumor and immunostimulatory effects
Journal for ImmunoTherapy of Cancer·2015· 1 citedOpen Access
Anti-CD20-interferon-alpha fusion protein has superior in vivo activity against human B-cell lymphomas compared to rituximab and enhanced complement-dependent cytotoxicity in vitro.
Journal of Clinical Oncology·2013· 1 cited
Antibody-CD20-interferon-alpha fusion protein has superior in vivo activity against human B cell lymphomas compared to Rituximab, and enhanced complement-dependent cytotoxicity in vitro
Journal for ImmunoTherapy of Cancer·2013· 2 citedOpen Access
A novel modality of BAFF-specific inhibitor AMG623 peptibody reduces B-cell number and improves outcomes in murine models of autoimmune disease.
PubMed·2012· 47 cited
Anti-CD20-Interferon-α Fusion Protein Demonstrates Potent Direct Growth Inhibition, Antibody-Dependent Cellular Cytotoxicity, and Enhanced Complement-Dependent Cytotoxicity Against Human B Cell Lymphomas In Vitro, and Activity Against Multiple Human NHL Xenografts In Vivo
Blood·2011
Activity of anti-CD20-interferon-α fusion protein against human B-cell lymphomas.
Journal of Clinical Oncology·2011Open Access
Pharmacodynamic Effects of the Murine p75-Fc Fusion Protein in Mice
Journal of Investigative Dermatology Symposium Proceedings·2007· 12 citedOpen Access
Spontaneous Inflammatory Disease in HLA-B27 Transgenic Mice Does Not Require Transporter of Antigenic Peptides
Clinical Immunology·2001· 21 cited
The role of TALL-1 and APRIL in immune regulation
Trends in Immunology·2001· 34 cited
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS
International Immunology·2000· 134 citedOpen Access
Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation
The Journal of Experimental Medicine·2000· 248 citedOpen Access
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
Proceedings of the National Academy of Sciences·2000· 136 cited
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
Proceedings of the National Academy of Sciences·2000· 572 citedOpen Access
HLA-B27 transgenic mice are susceptible to collagen-induced arthritis: type II collagen as a potential target in human disease
Human Immunology·2000· 7 cited
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Frequent Co-authors

Harvinder S. Luthra(12), Chella S. David(12), Kristopher K. Steward(7), Christopher J. Krco(6), Marie Griffiths(6), Raj Sachdev(6), John M. Timmerman(5), Reiko Yamada(5), Sherie L. Morrison(5), Kent Miner(4), Hailing Hsu(4), H. S. Luthra(4), C S David(4), Miguel Á. González‐Gay(4), Eric Zanelli(4), Gataree Ngarmchamnanrith(4), Tadahiko Kohno(3), Susan McCabe(3), Nessa Hawkins(3), John Delaney(3)